ALLOCATING SAMPLE ANALYSIS TASKS TO ANALYTICAL DEVICES TO COMPLY WITH CONTROL TARGET
Granted: April 11, 2024
Application Number:
20240118252
In a method of allocating a plurality of functional tasks to a plurality of functional devices each capable of carrying out one or more of the functional tasks, the functional devices are analytical devices and each of the functional tasks corresponds to a respective predefined process related to analyzing a respective sample by a respective one of the functional devices. The functional tasks are allocated to the functional devices based on a criterion to achieve compliance with at least…
MULTILAYER COATING FOR INTERFACE CONES
Granted: March 21, 2024
Application Number:
20240093353
A multilayer coating including an adhesion layer; and a protective coating is disclosed. The multilayer coating can be applied to a portion of at least one of a base and a tip of an interface cone. A method of making a coated interface cone is also disclosed.
FLUID DELIVERY DEVICE WITH PASSIVE PRESSURE EQUILIBRATION
Granted: February 22, 2024
Application Number:
20240058813
A fluid delivery device is configured to create a pressure differential across a compartment in which a liquid resides, causing the liquid to flow through the compartment. After a period of time, the fluid delivery device is configured to eliminate the pressure differential and thereby equilibrate the pressure across the compartment, with the use of a pressure equilibration channel that is separate from the compartment. The compartment may contain a packed bed of solid phase particles…
FILTER ASSEMBLIES, DEPTH INDICATORS, TORQUE-LIMITING FITTINGS, TORQUE-INDICATING FITTINGS, AND SYSTEMS INCORPORATING THE SAME
Granted: February 22, 2024
Application Number:
20240058731
In some examples, a system may include a housing attachable to a column and including a turn fitting and a receiver. The turn fitting may be movable relative to the receiver and along an axis of the housing between a neutral state and an attached state. In the neutral state, the turn fitting may be disposed at a first axial location along the axis of the housing. In the attached state, the turn fitting may be disposed at a second axial location along the axis of the housing.
AXIALLY PROGRESSIVE LENS FOR TRANSPORTING CHARGED PARTICLES
Granted: February 1, 2024
Application Number:
20240038521
An electrostatic lens for transporting charged particles in an axial direction includes a first group of first electrodes configured to receive a first DC potential from a DC voltage source, and a second group of second electrodes configured to receive a second DC potential from the DC voltage source different from the first DC potential. The first electrodes are interdigitated with the second electrodes. The first group and/or the second group has a geometric feature that progressively…
AXIALLY PROGRESSIVE LENS FOR TRANSPORTING CHARGED PARTICLES
Granted: February 1, 2024
Application Number:
20240038521
An electrostatic lens for transporting charged particles in an axial direction includes a first group of first electrodes configured to receive a first DC potential from a DC voltage source, and a second group of second electrodes configured to receive a second DC potential from the DC voltage source different from the first DC potential. The first electrodes are interdigitated with the second electrodes. The first group and/or the second group has a geometric feature that progressively…
ION FUNNEL-BASED COLLISION CELL
Granted: February 1, 2024
Application Number:
20240038520
In some examples, an ion funnel-based collision cell may include an ion funnel entrance section formed by a plurality of adjacently disposed entrance members. Each entrance member of at least one pair of the adjacently disposed entrance members may include a successively larger opening to form a tapered or profiled entrance for ions entering the ion funnel-based collision cell. An insulation material may be disposed adjacent to or in contact with each entrance member of the at least one…
MULTIPOLE SECTION-BASED ION FUNNEL
Granted: February 1, 2024
Application Number:
20240038519
In some examples, a multipole section-based ion funnel may include an ion funnel section formed by at least one pair of adjacently disposed members. A first member of the at least one pair of adjacently disposed members may include a pole structure. A second member of the at least one pair of adjacently disposed members may include a pole structure that is engageable with the pole structure of the first member to form a multipole structure.
APPARATUS AND METHOD FOR DETERRING A THIRD PARTY FROM COPYING A PRODUCT OR PROCESS
Granted: February 1, 2024
Application Number:
20240037968
In some examples, deterring a third party from copying a product or process may include scanning code to generate scanned code. Text in the scanned code may be read and/or at least one image in the scanned code may be recognized. The text and/or the at least one image may be analyzed to determine whether the code includes a specified trademark. Based on a determination that the code includes the specified trademark, an indication of authenticity of the code may be generated.
ION FUNNEL-BASED COLLISION CELL
Granted: February 1, 2024
Application Number:
20240038520
In some examples, an ion funnel-based collision cell may include an ion funnel entrance section formed by a plurality of adjacently disposed entrance members. Each entrance member of at least one pair of the adjacently disposed entrance members may include a successively larger opening to form a tapered or profiled entrance for ions entering the ion funnel-based collision cell. An insulation material may be disposed adjacent to or in contact with each entrance member of the at least one…
MULTIPOLE SECTION-BASED ION FUNNEL
Granted: February 1, 2024
Application Number:
20240038519
In some examples, a multipole section-based ion funnel may include an ion funnel section formed by at least one pair of adjacently disposed members. A first member of the at least one pair of adjacently disposed members may include a pole structure. A second member of the at least one pair of adjacently disposed members may include a pole structure that is engageable with the pole structure of the first member to form a multipole structure.
APPARATUS AND METHOD FOR DETERRING A THIRD PARTY FROM COPYING A PRODUCT OR PROCESS
Granted: February 1, 2024
Application Number:
20240037968
In some examples, deterring a third party from copying a product or process may include scanning code to generate scanned code. Text in the scanned code may be read and/or at least one image in the scanned code may be recognized. The text and/or the at least one image may be analyzed to determine whether the code includes a specified trademark. Based on a determination that the code includes the specified trademark, an indication of authenticity of the code may be generated.
COMPOSITIONS AND METHODS FOR GENOMIC DNA AND GENE EXPRESSION ANALYSIS IN SINGLE CELLS
Granted: January 11, 2024
Application Number:
20240011025
Provided herein are compositions and methods to assess the genomic landscape of fixed cells using light activated oligonucleotides that can be directed to the nucleus, mitochondria, or cytoplasm of fixed cells and that, upon activation, can be extended for in situ copying of nuclear single-stranded DNA (i.e., open chromatin), open mitochondrial DNA, and/or cytoplasmic RNA into barcoded complementary DNA. These methods also provide for gene specific 3D chromatin structural niche analysis.
COMPOSITIONS AND METHODS FOR GENOMIC DNA AND GENE EXPRESSION ANALYSIS IN SINGLE CELLS
Granted: January 11, 2024
Application Number:
20240011025
Provided herein are compositions and methods to assess the genomic landscape of fixed cells using light activated oligonucleotides that can be directed to the nucleus, mitochondria, or cytoplasm of fixed cells and that, upon activation, can be extended for in situ copying of nuclear single-stranded DNA (i.e., open chromatin), open mitochondrial DNA, and/or cytoplasmic RNA into barcoded complementary DNA. These methods also provide for gene specific 3D chromatin structural niche analysis.
UNIVERSAL MULTI-DETECTION SYSTEM FOR MICROPLATES WITH CONFOCAL IMAGING
Granted: January 4, 2024
Application Number:
20240003810
An apparatus for optically analyzing a sample may include an imaging subsystem that images the sample, one or more analyzing subsystems that analyze the sample including a confocal imaging subsystem, a temperature control subsystem that controls a temperature of the atmosphere within the apparatus, a gas control subsystem that controls a composition of the atmosphere within the apparatus, and a control module that controls the various subsystems of the apparatus.
LOAD ADAPTER FOR IMPROVED PACKING BED STABILITY
Granted: December 28, 2023
Application Number:
20230417710
In some examples, a load adapter may include a body including an elongated shaft that includes an inlet passage that is in fluid communication with at least one outlet hole. The at least one outlet hole may be dimensioned to provide an opening area that is between approximately 5% to approximately 90% of a face of the body.
DEVICE INCLUDING TRANSPARENT POLYMER WITH HYDROPHILIC COATING, AND METHOD OF MAKING SAME
Granted: December 14, 2023
Application Number:
20230399744
A device, including a hydrophilic layer on a portion of an inner surface of a transparent polymer forming a body; wherein the hydrophilic layer includes a sulfonated inner surface of the transparent polymer, a silica, a silicon oxycarbide, an O2 plasma treatment of the transparent polymer, or a combination thereof. The device can be a nebulizer or a spray chamber, for example used in an inductively coupled plasma device. A method of making the device is also disclosed.
COLUMN DEPTH MEASURING GUIDE
Granted: November 30, 2023
Application Number:
20230384079
A device, including a body including a first post and a second post positioned on opposite sides of a recessed area is disclosed. An assembly including the device is disclosed. A method of using the device is also disclosed.
MICROFLUIDIC CHIP-BASED DROPLET PROCESSOR
Granted: November 9, 2023
Application Number:
20230356226
A microfluidic apparatus for forming one or more droplets of an aqueous fluid suspended in a non-aqueous fluid is described. The microfluidic apparatus includes a first microfluidic channel configured for flowing an aqueous fluid through the first microfluidic channel and a second microfluidic channel fluidically connected to the first microfluidic channel and adapted to flow a non-aqueous fluid through the second microfluidic channel into the first microfluidic channel. A microfluidic…
RESISTIVE COATING FOR A CAPILLARY
Granted: October 5, 2023
Application Number:
20230313366
A coated capillary tube having a tunable resistance in an ion transfer device, including an inlet end in communication with an atmospheric-pressure ion source, an outlet end in communication with a vacuum region of a mass spectrometer, a body elongated along an axis from the inlet end to the outlet end, and an inside surface defining a bore having an inner diameter is disclosed. The coated capillary tube also includes a resistive coating on the inside surface of the capillary tube, in…
