METHOD OF PRODUCING ETCHED NON-POROUS PARTICLES
Granted: September 28, 2023
Application Number:
20230303398
There is disclosed a method of producing etched non-porous particles. The method includes, in some examples, coating a non-porous particle with a hydrophilic polymer and treating the coated particle with acid or base. Also provided is etched non-porous particles capable of separating a variety of analytes, including biomolecules.
CHROMATOGRAPHY COLUMN
Granted: August 24, 2023
Application Number:
20230264118
A chromatography column includes a first flow distributor, a second flow distributor, and a media chamber having an inlet and an outlet. The second flow distributor is different from the first flow distributor. The first flow distributor is secured to the inlet of the media chamber and the second flow distributor is secured to the outlet of the media chamber.
METAL COMPONENTS WITH INERT VAPOR PHASE COATING ON INTERNAL SURFACES
Granted: July 13, 2023
Application Number:
20230220542
The invention provides metal liquid chromatography components with uniformly coated internal surfaces and methods for achieving the same. The invention addresses the problem of corrosion or interference of metal components in the flow path for LC analyses in which the sample interacts with metal ions or surfaces. The invention also alleviates the difficulties in coating very long metal tubes and very small metal channels with an inert, continuous coating that adheres well to metal…
INSTRUMENT CLOSURE INCLUDING SENSOR RETAINER
Granted: June 22, 2023
Application Number:
20230192364
In some examples, an instrument closure may include an instrument closure retainer to retain the instrument closure onto a container. The instrument closure may further include a sensor retainer including a plurality of apertures for transfer or removal of material, respectively, into or from the container. The sensor retainer may further include a sensor mount to retain a sensor.
METHODS AND SYSTEMS FOR SENSING HEADSPACE VIAL PRESENCE
Granted: May 25, 2023
Application Number:
20230160865
Methods and systems for sensing headspace vial presence are described herein. In one embodiment, a system can include a sample probe, a fluid source in fluid communication with the sample probe, one or more of a pressure sensor and a flow sensor in fluid communication with the sample probe, and a processor configured to: (a) receive a first set of signals from the one or more of the pressure and flow sensors, execute an ejection procedure to remove a sample vial from the sample probe,…
SAMPLE SEPARATION NETWORK WITH SIMPLY CONNECTABLE SAMPLE SEPARATION DEVICE
Granted: April 27, 2023
Application Number:
20230131152
A sample separation network includes a server node, a plurality of client nodes coupled with the server node, a plurality of sample separation devices coupled with the server node, wherein each of the sample separation devices includes device-specific control software configured for controlling specifically the respectively assigned sample separation device, wherein at least one of the server node and the client nodes includes generic control software configured for generically…
DUAL FEEDBACK LOOP FOR PRECISION HIGH VOLTAGE POWER SUPPLY
Granted: April 27, 2023
Application Number:
20230127124
A high-voltage (HV) power supply outputs an output voltage based on a control signal produced by a dual analog/digital feedback loop. The control signal is determined at least in part by an error amplifier that receives a measurement signal, proportionally attenuated from the output voltage, and a digital-to-analog converter (DAC) output signal. An analog-to-digital converter (ADC) also receives the measurement signal and transmits it in digitized form to a digital processor. The digital…
ION ACTIVATION AND FRAGMENTATION IN SUB-AMBIENT PRESSURE FOR ION MOBILITY AND MASS SPECTROMETRY
Granted: April 27, 2023
Application Number:
20230126290
An ion source may include an ionization chamber to be maintained at atmospheric-pressure. The ion source may further include a reduced-pressure chamber to be maintained at sub-atmospheric pressure, and an ion transfer device comprising an inlet in the ionization chamber and an outlet in the reduced-pressure chamber. The ion transfer device may define an ion path from the inlet to the outlet. The ion transfer device may be positioned to emit ions and neutral gas molecules from the outlet…
FILTER ASSEMBLIES, DEPTH INDICATORS, TORQUE-LIMITING FITTINGS, TORQUE-INDICATING FITTINGS, AND SYSTEMS INCORPORATING THE SAME
Granted: April 13, 2023
Application Number:
20230110390
In some examples, a filter assembly may include a filter including a first gasket having a first channel adjacent to a first side of the filter and a second gasket having a second channel adjacent to a second side of the filter. The first gasket and the second gasket may include a beveled surface adjacent to the filter. The first channel and the second channel may include a diameter of from about 0.01 mm to about 0.5 mm. A finger tightening system may securely hold the filter without any…
ION GUIDE WITH VARYING MULTIPOLES
Granted: February 23, 2023
Application Number:
20230055007
An ion guide includes electrodes elongated along an axis from an entrance end to an exit end and spaced around the axis to surround an interior. The electrodes have polygonal shapes with inside surfaces disposed at a radius from the axis and having an electrode width tangential to a circle inscribed by the electrodes. An aspect ratio of the electrode width to the radius varies along the axis. The electrodes are configured to generate a two-dimensional RF electrical field in the interior…
METHODS OF MAKING POROUS DEVICES FROM MONODISPERSE POPULATIONS OF POLYARYLKETONE OR POLYARYLTHIOETHERKETONE PARTICLES
Granted: February 16, 2023
Application Number:
20230052045
The invention provides methods for making porous devices from substantially monodisperse populations of substantially spherical particles of polyarylketone polymers or of thio-analogues of such polymers, of selected sizes. The porous devices allow greater control of porosity than previously available porous devices. In some embodiments, the porous devices are frits, filters, membranes or monoliths.
METHODS OF MAKING MONODISPERSE POPULATIONS OF POLYARYLKETONE OR POLYARYLTHIOETHERKETONE PARTICLES
Granted: February 16, 2023
Application Number:
20230051959
The invention provides methods for making substantially monodisperse populations of substantially spherical particles of polyarylketone polymers or of thio-analogues of such polymers, of selected sizes. Populations of such particles can be used, for example, to form porous devices with greater control of porosity than previously available. In some embodiments, the porous devices are frits, filters, membranes or monoliths.
METHODS OF MAKING MEDIA OF SUBSTANTIALLY MONODISPERSE POPULATIONS OF POLYARYLKETONE OR POLYARYLTHIOETHERKETONE PARTICLES, AND CONTAINERS COMPRISING THEM
Granted: February 16, 2023
Application Number:
20230047460
The invention provides separation media of substantially monodisperse populations of substantially spherical particles of polyarylketone polymers or of thio-analogues of such polymers, of selected sizes, and further provides containers, such as chromatographic columns and cartridges, containing substantially monodisperse populations of such particles.
METHODS OF MAKING POROUS DEVICES FROM MONODISPERSE POPULATIONS OF POLYARYLKETONE OR POLYARYLTHIOETHERKETONE PARTICLES
Granted: February 16, 2023
Application Number:
20230052045
The invention provides methods for making porous devices from substantially monodisperse populations of substantially spherical particles of polyarylketone polymers or of thio-analogues of such polymers, of selected sizes. The porous devices allow greater control of porosity than previously available porous devices. In some embodiments, the porous devices are frits, filters, membranes or monoliths.
METHODS OF MAKING MONODISPERSE POPULATIONS OF POLYARYLKETONE OR POLYARYLTHIOETHERKETONE PARTICLES
Granted: February 16, 2023
Application Number:
20230051959
The invention provides methods for making substantially monodisperse populations of substantially spherical particles of polyarylketone polymers or of thio-analogues of such polymers, of selected sizes. Populations of such particles can be used, for example, to form porous devices with greater control of porosity than previously available. In some embodiments, the porous devices are frits, filters, membranes or monoliths.
METHODS OF MAKING MEDIA OF SUBSTANTIALLY MONODISPERSE POPULATIONS OF POLYARYLKETONE OR POLYARYLTHIOETHERKETONE PARTICLES, AND CONTAINERS COMPRISING THEM
Granted: February 16, 2023
Application Number:
20230047460
The invention provides separation media of substantially monodisperse populations of substantially spherical particles of polyarylketone polymers or of thio-analogues of such polymers, of selected sizes, and further provides containers, such as chromatographic columns and cartridges, containing substantially monodisperse populations of such particles.
METHODS OF MAKING POROUS DEVICES FROM MONODISPERSE POPULATIONS OF POLYARYLKETONE OR POLYARYLTHIOETHERKETONE PARTICLES
Granted: February 16, 2023
Application Number:
20230052045
The invention provides methods for making porous devices from substantially monodisperse populations of substantially spherical particles of polyarylketone polymers or of thio-analogues of such polymers, of selected sizes. The porous devices allow greater control of porosity than previously available porous devices. In some embodiments, the porous devices are frits, filters, membranes or monoliths.
METHODS OF MAKING MONODISPERSE POPULATIONS OF POLYARYLKETONE OR POLYARYLTHIOETHERKETONE PARTICLES
Granted: February 16, 2023
Application Number:
20230051959
The invention provides methods for making substantially monodisperse populations of substantially spherical particles of polyarylketone polymers or of thio-analogues of such polymers, of selected sizes. Populations of such particles can be used, for example, to form porous devices with greater control of porosity than previously available. In some embodiments, the porous devices are frits, filters, membranes or monoliths.
METHODS OF MAKING MEDIA OF SUBSTANTIALLY MONODISPERSE POPULATIONS OF POLYARYLKETONE OR POLYARYLTHIOETHERKETONE PARTICLES, AND CONTAINERS COMPRISING THEM
Granted: February 16, 2023
Application Number:
20230047460
The invention provides separation media of substantially monodisperse populations of substantially spherical particles of polyarylketone polymers or of thio-analogues of such polymers, of selected sizes, and further provides containers, such as chromatographic columns and cartridges, containing substantially monodisperse populations of such particles.
MULTI-DEVICE REMOVAL AND INSTALLATION TOOL
Granted: January 19, 2023
Application Number:
20230017417
In some examples, a multi-device removal and installation tool may include a device removal tool including a first side having a first receiver with a first dimension that removably receives a first device, and a second side having a second receiver with a second dimension that removably receives a second device. The first dimension may be different from the second dimension. A torque limit tool may apply, in a first rotation direction of the torque limit tool and the device removal…
