FUNDAMENTALS OF SEMI-CONDUCTOR-BASED PHOTON COUNTING DETECTORS
Granted: October 24, 2024
Application Number:
20240350833
Disclosed herein is a treatment apparatus. The treatment apparatus includes a rotatable gantry system positioned at least partially around a patient support and a first source of radiation coupled to the rotatable gantry system. The first source of radiation is configured to emit imaging x-ray radiation after pausing for a time interval between periodic emissions. The apparatus further includes a radiation detector configured to receive x-ray radiation from the first radiation source and…
Heteroaryl Derivative, Preparation Method Therefor, And Use Thereof
Granted: November 2, 2023
Application Number:
20230348467
The present invention relates to heteroaryl derivatives, preparation methods therefor, and applications thereof in medicine. Specifically, the present invention relates to a heteroaryl derivative represented by general formula (AI), a preparation method therefor, and a pharmaceutically acceptable salt, and use thereof as a therapeutic agent, in particular, as an SHP2 allosteric inhibitor, wherein the definition of substituents in general formula (AI) is the same as that in the…
METHODS FOR SATURATION CORRECTION AND DYNAMIC GAIN CONFIGURATION AND APPARATUSES FOR PERFORMING THE SAME
Granted: August 10, 2023
Application Number:
20230248329
Saturation in at least one saturated ray is in a method including identifying a saturated ray corresponding to a first ray of a radiation source received at a radiation detector after passing through a reference point during a current view of the radiation detector, identifying at least one non-saturated ray corresponding to a second ray of the radiation source received at the radiation detector, and responsive to the identifying, adjusting a value for the saturated ray based on a value…
MULTIMODAL RADIATION APPARATUS AND METHODS
Granted: January 19, 2023
Application Number:
20230017353
An imaging apparatus comprises a rotatable gantry system positioned at least partially around a patient support; a first source of radiation coupled to the rotatable gantry system, the first source of radiation configured for imaging radiation; a second source of radiation coupled to the rotatable gantry system; and a first radiation detector coupled to the rotatable gantry system and laterally movable relative to a central beam of the first source of radiation to receive radiation from…
MULTIMODAL RADIATION APPARATUS AND METHODS
Granted: January 19, 2023
Application Number:
20230017353
An imaging apparatus comprises a rotatable gantry system positioned at least partially around a patient support; a first source of radiation coupled to the rotatable gantry system, the first source of radiation configured for imaging radiation; a second source of radiation coupled to the rotatable gantry system; and a first radiation detector coupled to the rotatable gantry system and laterally movable relative to a central beam of the first source of radiation to receive radiation from…
RADIOTHERAPY APPARATUS AND METHODS FOR TREATMENT AND IMAGING USING HYBRID MeV-keV, MULTI-ENERGY DATA ACQUISITION FOR ENHANCED IMAGING
Granted: December 15, 2022
Application Number:
20220395243
A radio therapy system includes a first x-ray source. The first x-ray source is configured to produce first x-ray photons in a first energy range suitable for imaging and project the first x-ray photons onto an area designated for imaging. The system includes a second x-ray source configured to produce second x-ray photons in a second energy range higher energy than the first energy range, produce third x-ray photons in a third energy range higher energy than the first energy range,…
MULTIMODAL RADIATION APPARATUS AND METHODS
Granted: January 6, 2022
Application Number:
20220000443
A multimodal imaging apparatus, comprising a rotatable gantry system positioned at least partially around a patient support, a first source of radiation coupled to the rotatable gantry system, the first source of radiation configured for imaging radiation, a second source of radiation coupled to the rotatable gantry system, the second source of radiation configured for at least one of imaging radiation or therapeutic radiation, wherein the second source of radiation has an energy level…
FRAMELESS RADIOSURGERY TREATMENT SYSTEM AND METHOD
Granted: April 17, 2014
Application Number:
20140107477
A method of compensating for breathing and other motions of a patient during treatment includes periodically generating internal positional data about an internal target region. The method further includes generating external positional data about external motion of the patient's body using an external sensor and generating a correlation between one or more positions of the internal target region and one or more positions of an external region using the external positional data of the…
MAGNETRON POWERED LINEAR ACCELERATOR FOR INTERLEAVED MULTI-ENERGY OPERATION
Granted: November 28, 2013
Application Number:
20130315379
The disclosure relates to systems and methods for interleaving operation of a linear accelerator that use a magnetron as the source of electromagnetic waves for use in accelerating electrons to at least two different ranges of energies. The accelerated electrons can be used to generate x-rays of at least two different energy ranges. In certain embodiments, the accelerated electrons can be used to generate x-rays of at least two different energy ranges. The systems and methods are…
INTERLEAVING MULTI-ENERGY X-RAY ENERGY OPERATION OF A STANDING WAVE LINEAR ACCELERATOR
Granted: March 14, 2013
Application Number:
20130063052
The disclosure relates to systems and methods for interleaving operation of a standing wave linear accelerator (LINAC) for use in providing electrons of at least two different energy ranges, which can be contacted with x-ray targets to generate x-rays of at least two different energy ranges. The LINAC can be operated to output electrons at different energies by varying the power of the electromagnetic wave input to the LINAC, or by using a detunable side cavity which includes an…
Image Registration for Image-Guided Surgery
Granted: January 17, 2013
Application Number:
20130016889
An image registration process for detecting a change in position of a surgical target, such as a tumor, within a patient is disclosed. A pre-operative model of the target and surrounding area is generated, then registered to live patient images to determine or confirm a location of the target during the course of surgery. Image registration is based on a non-iterative image processing logic that compares a similarity measure for a template of the target (generated from the pre-operative…
Ring Gantry Radiation Treatment Delivery System With Dynamically Controllable Inward Extension Of Treatment Head
Granted: July 26, 2012
Application Number:
20120189102
Systems, methods, and related computer program products for image-guided radiation treatment (IGRT) are described. For one preferred embodiment, an IGRT apparatus is provided comprising a ring gantry having a central opening sufficiently large to accommodate a body of a patient positioned along a longitudinal axis and extending therethrough, and a gantry tilting mechanism configured to tilt the ring gantry to a plurality of different tilt angles relative to the longitudinal axis. A…
TRAVELING WAVE LINEAR ACCELERATOR BASED X-RAY SOURCE USING CURRENT TO MODULATE PULSE-TO-PULSE DOSAGE
Granted: April 5, 2012
Application Number:
20120081042
Provided herein are systems and methods for operating a traveling wave linear accelerator to generate stable electron beams at two or more different intensities by varying the number of electrons injected into the accelerator structure during each pulse by varying the electron beam current applied to an electron gun.
TRAVELING WAVE LINEAR ACCELERATOR BASED X-RAY SOURCE USING PULSE WIDTH TO MODULATE PULSE-TO-PULSE DOSAGE
Granted: April 5, 2012
Application Number:
20120081041
Provided herein are systems and methods for operating a traveling wave linear accelerator to generate stable electron beams at two or more different intensities by varying the number of electrons injected into the accelerator structure during each pulse by varying the width of the beam pulse, i.e., pulse width.
IMAGE ALIGNMENT
Granted: March 22, 2012
Application Number:
20120069968
A method and apparatus for positioning a patient for radiation treatment are described. The method includes obtaining a plurality of projection images of a patient positioned on a treatment couch, displaying at least one of the plurality of projection images with a corresponding synthetic projection image on a display, adjusting the position of the at least one projection image on the display to approximately align with the corresponding synthetic projection image in response to a user…
RADIATION TREATMENT DELIVERY SYSTEM WITH OUTWARDLY MOVABLE RADIATION TREATMENT HEAD EXTENDING FROM RING GANTRY
Granted: February 9, 2012
Application Number:
20120035470
Systems, methods, and related computer program products for image-guided radiation treatment (IGRT) are described. For one preferred embodiment, an IGRT apparatus is provided comprising a gantry frame including a ring member, the ring member being rotatable around a substantially horizontal, longitudinally extending central axis, the ring member having first and second horizontally opposing ends. The IGRT apparatus further comprises a radiation treatment head coupled to the ring member…
Target Tracking for Image-Guided Radiation Treatment
Granted: January 12, 2012
Application Number:
20120008734
Systems, methods, and related computer program products for medical imaging and image-guided radiation treatment (IGRT) are described. In one preferred embodiment, an IGRT system provides intrafraction target tracking based on a comparison of intrafraction x-ray tomosynthesis image data with initial x-ray tomosynthesis image data acquired with the patient in an initial treatment position, the initial x-ray tomosynthesis image data having an inherent registration with co-acquired image…
Imaging Methods for Image-Guided Radiation Treatment
Granted: January 12, 2012
Application Number:
20120008735
Systems, methods, and related computer program products for medical imaging and image-guided radiation treatment (IGRT) are described. In one embodiment, an IGRT system selectively integrates x-ray source arrays, dual-energy imaging, stereoscopic imaging, static and dynamic source collimation, and/or inverse geometry tomosynthesis imaging to acquire and/or track a target during radiation treatment. Advantages include reduced patient x-ray dose and/or reduced treatment delivery margins.
Radiation Treatment Delivery System With Translatable Ring Gantry
Granted: December 8, 2011
Application Number:
20110301449
Systems, methods, and related computer program products for image-guided radiation treatment (IGRT) are described. For one preferred embodiment, an IGRT apparatus is provided comprising a ring gantry having a central opening and a radiation treatment head coupled to the ring gantry that is rotatable around the central opening in at least a 180 degree arc. For one preferred embodiment, the apparatus further comprises a gantry translation mechanism configured to translate the ring gantry…
Gantry Image Guided Radiotherapy System And Related Treatment Delivery Methods
Granted: September 1, 2011
Application Number:
20110211665
Systems, methods, and related computer program products for image-guided radiation treatment (IGRT) are described. Provided according to one preferred embodiment is an IGRT apparatus including a barrel-style rotatable gantry structure that provides high mechanical stability, versatility in radiation delivery, and versatility in target tracking. Methods for treatment radiation delivery using the IGRT apparatus include conical non-coplanar rotational arc therapy and cono-helical…
