LIQUID CHROMATOGRAPHY STANDARD COMPOSITION
Granted: January 30, 2025
Application Number:
20250035596
A composition, including an alkaloid, and a diaryl ketone is disclosed. Also, disclosed is a kit including one or more containers in which each of the one or more containers includes the composition. A method of using a standard composition is also disclosed.
SYSTEM AND METHOD FOR VARIABLE SIZE CONTAINER HANDLING
Granted: January 23, 2025
Application Number:
20250026572
In some examples, a system may include at least two conveyors disposed at a specified distance apart and movable toward each other to reduce the specified distance or away from each other to increase the specified distance. The at least two conveyors may be operable to move a container that is contiguously disposable between the at least two conveyors along a first direction when the at least two conveyors are operated in the first direction and along a second direction that is opposite…
SOFTWARE LICENSING MANAGEMENT AND AUTHENTICATION
Granted: January 2, 2025
Application Number:
20250005113
Novel tools and techniques are provided for implementing software licensing management and authentication. In various examples, a computing system might receive a request for an unlock code for a requested service from a user using a client device on which a first software is executed, the request comprising a generated unique identifier associated with the requested service and/or the first software. The generated unique identifier comprises licensing information associated with the…
Chemically Modified Guide RNAs for CRISPR/CAS-Mediated Gene Correction
Granted: December 5, 2024
Application Number:
20240401034
Provided herein are methods for inducing CRISPR/Cas-based gene regulation (e.g., genome editing or gene expression) of a target nucleic acid (e.g., target DNA or target RNA) in a cell. The methods include using modified single guide RNAs (sgRNAs) that enhance gene regulation of the target nucleic acid in a primary cell for use in ex vivo therapy or in a cell in a subject for use in in vivo therapy. Additionally, provided herein are methods for preventing or treating a genetic disease in…
THREE-DIMENSIONAL PRINTED NANOSPRAY INTERFACE FOR MASS SPECTROMETRY
Granted: November 28, 2024
Application Number:
20240395525
In some examples, a three-dimensional printed nanospray interface for mass spectrometry may include a body including a sheath inlet connected to a sheath outlet for passage of sheath liquid to an emitter. The emitter may include a sidewall including a stepped texture on an inner surface of the sidewall.
ADVECTION-BASED TRANSPORT OF ABLATED MATERIAL
Granted: November 7, 2024
Application Number:
20240371623
In some examples, an apparatus may include an advection flow structure including a passage to transport, via advection by a gas flow, an ablated sample from an ablation region to an ionization region.
ION SOURCE
Granted: October 10, 2024
Application Number:
20240339313
Provided herein is an ion source containing a plurality of components, at least one of which is partially coated with a layer of silicon. The ion source reduces reactivity between the sample and the carrier gas, reduces or eliminates tailing in ion chromatograms, and/or improves mass spectral fidelity. Also provided are methods of using the ion source in a mass spectrometer or gas chromatograph-mass spectrometer.
IMMUNOHISTOCHEMISTRY (IHC) PROTOCOLS AND METHODS FOR DIAGNOSING AND TREATING CANCER
Granted: September 5, 2024
Application Number:
20240295559
In alternative embodiments, provided are immunohistochemistry (IHC) methods for determining and scoring reproducibly the extent of nuclear expression of protein Ki-67 (also known as MK167) in a tissue sample. In alternative embodiments, provided are methods for diagnosing, treating or ameliorating or assessing the risk of recurrence for a cancer or a tumor using an IHC method as provided herein. In alternative embodiments, provided are kits comprising components and instructions for…
3D CELL WASHER
Granted: August 1, 2024
Application Number:
20240254982
An autoclaving microplate washing system for cells and non-adhering three-dimensional (3D) cell cultures includes one or more pumps for controlling the dispensing of washing fluid and the evacuation of fluid from microwells to gently wash the cells. A method of controlling the autoclaving microplate washing system includes controlling the one or more pumps for dispensing and evacuation.
LINEAR AND NON-LINEAR RANGE-BASED PLOT PANE SELECTION
Granted: July 25, 2024
Application Number:
20240248580
In some examples, linear and non-linear range-based plot pane selection may include receiving data that is to be displayed. Based on an increase or a decrease in a size of a range selector, a selection of a range of plot panes may be received from a plurality of available plot panes to display the data. Based on the received selection of the range of plot panes, a display of the data may be generated in plot panes included in the range of plot panes. The size of the range selector may be…
MULTI-DEVICE REMOVAL AND INSTALLATION TOOL
Granted: July 18, 2024
Application Number:
20240238952
In some examples, a multi-device removal and installation tool may include a device removal tool including a first side having a first receiver with a first dimension that removably receives a first device, and a second side having a second receiver with a second dimension that removably receives a second device. The first dimension may be different from the second dimension. Further, the first receiver may include a plurality of separators to separate a surface of the first receiver…
VESSEL MOUNTING SYSTEM
Granted: July 11, 2024
Application Number:
20240229851
In some examples, a vessel mounting system may include a first collar and a second collar. The second collar may include a clip engageable with an edge of the first collar to engage the second collar with the first collar.
VESSEL MOUNTING SYSTEM
Granted: July 11, 2024
Application Number:
20240229850
In some examples, a vessel mounting system may include a first collar including at least one protrusion engageable with a groove of a vessel to align the first collar relative to the vessel. A second collar may include at least one stud disposable in a corresponding aperture of the first collar to align the second collar relative to the first collar.
VESSEL MOUNTING SYSTEM
Granted: July 11, 2024
Application Number:
20240229848
In some examples, a vessel mounting system may include a first collar including at least one flexible member engageable with a groove of a vessel to align the first collar relative to the vessel. A second collar may include at least one clip engageable with a complementary clip of the first collar to engage the second collar with the first collar.
VESSEL MOUNTING SYSTEM
Granted: July 11, 2024
Application Number:
20240226901
In some examples, a vessel mounting system may include a first collar and a second collar. The second collar may include at least one positioning member to position the second collar relative to the first collar. Further, the second collar may include at least one interlocking member to lock the second collar to the first collar.
MULTI-DEVICE REMOVAL AND INSTALLATION TOOL
Granted: June 20, 2024
Application Number:
20240203721
In some examples, a multi-device removal and installation tool may include a device removal tool including catch members engageable with an engagement face of a device to attach, upon engagement of the catch members with the engagement face, the device removal tool to the device. The catch members may engage the engagement face with a removal force that is sufficient to remove, upon engagement of the catch members with the engagement face, the device from an instrument. The multi-device…
VESSEL MOUNTING SYSTEM
Granted: April 25, 2024
Application Number:
20240131519
In some examples, a vessel mounting system may include a first collar and a second collar. The second collar may include at least one positioning member to position the second collar relative to the first collar. Further, the second collar may include at least one interlocking member to lock the second collar to the first collar.
VESSEL MOUNTING SYSTEM
Granted: April 25, 2024
Application Number:
20240133412
In some examples, a vessel mounting system may include a first collar and a second collar. The second collar may include a clip engageable with an edge of the first collar to engage the second collar with the first collar.
VESSEL MOUNTING SYSTEM
Granted: April 25, 2024
Application Number:
20240133411
In some examples, a vessel mounting system may include a first collar including at least one protrusion engageable with a groove of a vessel to align the first collar relative to the vessel. A second collar may include at least one stud disposable in a corresponding aperture of the first collar to align the second collar relative to the first collar.
VESSEL MOUNTING SYSTEM
Granted: April 25, 2024
Application Number:
20240133410
In some examples, a vessel mounting system may include a first collar including at least one flexible member engageable with a groove of a vessel to align the first collar relative to the vessel. A second collar may include at least one clip engageable with a complementary clip of the first collar to engage the second collar with the first collar.
