PROGRAMMING LANGUAGE TRANSLATOR
Granted: December 30, 2010
Application Number:
20100333076
A computer readable medium stores a program, executable by a computer, for enabling translation of machine-centric commands in an instrument protocol to a programming language for controlling an instrument configured to use the machine-centric commands. The computer readable medium includes an identifying code segment for identifying instrument protocol commands executable by the instrument, and a generating code segment generates methods corresponding to the instrument protocol…
Micro-plasma Illumination Device and Method
Granted: December 30, 2010
Application Number:
20100327155
An illumination method and device has a micro-wave powered plasma source contained by a windowless plasma containment structure. When incorporated as a photo-ionization device in an ion mobility spectrometer (IMS), the resolution of the spectrometer may be improved by operation at higher pressures and through selective ionization of elements and compounds. A gas flows into a discharge gap of a micro-wave ring resonator, but is restricted from flowing away by the windowless containment…
METHOD AND APPARATUS FOR DETERMINING EQUALIZATION COEFFICIENTS
Granted: December 23, 2010
Application Number:
20100322299
A system for filtering a data signal includes an input configured to receive the data signal through a transmission medium and a filter configured to remove distortion from the received data signal using equalization coefficients. The system further includes a processing unit configured to determine dynamically the equalization coefficients of the filter without using a predetermined training pattern in the received data signal.
MEASUREMENT DEVICE WITH MOTION-TRIGGERED DATA EXCHANGE
Granted: December 16, 2010
Application Number:
20100314447
A measurement device (100) comprising an accommodation chamber (102) adapted for accommodating a replaceable measurement member (104), a movable closure mechanism (106) adapted to be moved to selectively expose or cover the accommodation chamber (102), and a data mechanism (600) adapted for at least one of reading data from and writing data on a replaceable measurement member (104), when the replaceable measurement member (104) is accommodated in the accommodation chamber (102), upon…
Atmospheric Inductively Coupled Plasma Generator
Granted: December 2, 2010
Application Number:
20100300620
In an atmospheric inductively coupled plasma generating apparatus, impedance matching between a coil for plasma generation and an RF power source is effected at a high speed. A control method and/or condition for the output frequency of an oscillator which supplies a power to the coil for plasma generation or a control method and a control condition for the output power of the oscillator are changed appropriately in accordance with a generation state of a plasma. When a plasma is not…
CONVERGING MULTIPOLE ION GUIDE FOR ION BEAM SHAPING
Granted: December 2, 2010
Application Number:
20100301210
A multipole ion guide comprises rods disposed about an axis, each of the rods having a first end and a second end remote from the first end. Each of the rods is disposed at a respective greater distance from the axis at the first end than at the second end. The multipole ion guide comprises means for applying a radio frequency (RF) voltage between adjacent pairs of rods, wherein the RF voltage creates a multipole field in a region between the rods; and means for applying a direct current…
FREQUENCY GENERATOR AND METHOD OF FREQUENCY GENERATION WITH MULTIPLE SAMPLING PHASE DETECTORS
Granted: November 25, 2010
Application Number:
20100295621
A device includes: a plurality of sampling phase detectors, each receiving a sampling signal and a VCO output signal and in response thereto outputting a beat signal representing a frequency and phase difference between the VCO output signal and the sampling signal; a frequency/phase detector receiving a reference signal and a combined beat signal produced by combining the beat signals, and in response thereto producing an error signal representing a phase difference between the…
SERIAL TYPE PUMP COMPRISING A HEAT EXCHANGER
Granted: November 25, 2010
Application Number:
20100299079
A pump unit comprises a primary piston pump, a secondary piston pump, and a flow path adapted for fluidically connecting in series the primary piston pump and the secondary piston pump. The pump unit's duty cycle comprises a delivery-and-fill phase, in which the primary piston pump supplies a flow of liquid to the secondary piston pump, and during the delivery-and-fill phase, the flow of liquid supplied by the primary piston pump is partly used for filling up the secondary piston pump…
Automated baseline removal of signal
Granted: November 18, 2010
Application Number:
20100292957
A system for estimating a baseline of a signal exhibits a signal generator and a processor. The signal generator is configured to generate a signal exhibiting a plurality of peaks and a baseline. The processor is configured to perform operations including determining an estimator indicating at least one region of the signal that exhibits a peak, determining a weight indicating at least one region of the signal that does not exhibit a peak based on the estimator, and estimating the…
System and method for performing tandem mass spectrometry analysis
Granted: November 18, 2010
Application Number:
20100288918
A system for performing tandem mass spectrometry (MS/MS) analysis of a sample includes a mass spectrometer and a processor. The mass spectrometer is configured to perform a mass spectrometry (MS) scan of an ionized sample to provide a mass of an observed peak corresponding to a precursor ion. The processor is configured to perform operations including determining whether the mass of the observed peak matches a mass of at least one of multiple expected peptides on a dynamic watch list,…
System and method for analyzing contents of sample based on quality of mass spectra
Granted: November 18, 2010
Application Number:
20100288917
A method of performing tandem mass spectrometry (MS/MS) for identifying contents of a sample includes performing a mass spectrometry (MS) scan of the sample to obtain an MS/MS mass spectrum; identifying a first precursor ion species in the MS mass spectrum; performing an initial MS/MS scan of the first precursor ion species to obtain an initial MS/MS mass spectrum; and determining whether the initial MS/MS mass spectrum has a quality acceptable for peptide sequencing. When the first…
SHEAR VALVE WITH DLC COMPRISING MULTI-LAYER COATED MEMBER
Granted: November 11, 2010
Application Number:
20100281959
A shear valve for use in a high performance liquid chromatography system, the shear valve comprising a first shear valve member and a second shear valve member, wherein at least one of the first and second shear valve members is adapted to be moved with respect to the other, one of the first and second shear valve members comprises a plurality of ports, and the other comprises at least one fluid path for fluidly coupling respective ones of the ports in dependency on a relative movement…
Detecting peaks in two-dimensional signals
Granted: November 11, 2010
Application Number:
20100283785
A system for detecting true peaks in a two-dimensional signal includes a two-dimensional separator and a processor. The two-dimensional separator is configured to perform separation of a sample to provide the two-dimensional signal. The processor is configured to identify candidate peaks of the two-dimensional signal based on local maxima of points on a surface defined by the two-dimensional signal, and to identify at least one true peak from the candidate peaks.
PRIMARY PISTON CORRECTION DURING TRANSFER
Granted: November 4, 2010
Application Number:
20100275678
A method for controlling operation of a pump unit, where the pump unit includes a primary piston pump having a primary piston and a secondary piston pump having a secondary piston. The primary piston pump is fluidically connected with the secondary piston pump. The primary piston pump includes an inlet valve and an outlet valve, and the pump unit operates periodically according to a pump cycle. The method includes determining a fluid pressure of fluid dispensed by the pump unit, and…
INTEGRATED FLOW CELL WITH SEMICONDUCTOR OXIDE TUBING
Granted: November 4, 2010
Application Number:
20100277722
An integrated flow cell, the flow cell comprising a semiconductor substrate, and a fluidic conduit having an at least partially transparent semiconductor oxide tubing, wherein the semiconductor oxide tubing is formed with the semiconductor substrate.
OVERPOWER PROTECTION CIRCUIT
Granted: November 4, 2010
Application Number:
20100277839
A power protection apparatus includes a PIN diode circuit and a solid state limiter. The PIN diode circuit is connected to a signal path for transporting RF signals between a first RF device and a second RF device, the PIN diode circuit including first and second PIN diodes having opposite polarities. The solid state limiter is configured to detect an overpower condition of an RF signal input from the second RF device on the signal path, and to trigger the PIN diode circuit in response…
SYSTEM AND METHOD FOR INTERACTIVE INSTRUMENT OPERATION AND AUTOMATION
Granted: November 4, 2010
Application Number:
20100281412
A system and method: provide a user interface to a user, the user interface including one or more objects representing a corresponding one or more instruments that are connected to the system; receive from a user a selection of one of the one or more instruments, made via the user interface; obtaining at the computer a file that describes commands to which the selected instrument responds; and present to the user via the user interface an indication of the commands to which the selected…
Syringe with Improved Plunger
Granted: October 28, 2010
Application Number:
20100270335
A plunger for a syringe used to inject gas and liquid chromatography samples has an end portion surrounded by a flexible sleeve. The sleeve forms a seal in the bore of a barrel traversed by the plunger, the bore being in fluid communication with a cannula attached to the end of the barrel. The plunger has an end surface that is exposed and is flush with an annular end surface of the sleeve. The plunger end surface, and not the sleeve, contacts the cannula upon injection and avoids…
VALVE BASED OR VISCOSITY BASED CONTROL OF A FLUID PUMP
Granted: October 14, 2010
Application Number:
20100260617
A pump control for controlling a fluid pump for pumping a fluid, the pump control comprising a pump oil path comprising an oil pump and at least one valve, the oil pump being adapted for pumping pump oil to the fluid pump, the at least one valve being arranged downstream of the oil pump, and a control unit adapted for controlling a pump oil pressure in the fluid pump by switching the at least one valve so that the fluid can be pumped in response to the pump oil pressure.
HPLC-SYSTEM WITH VARIABLE FLOW RATE
Granted: October 7, 2010
Application Number:
20100252502
In a high performance liquid chromatography system, wherein a mobile phase is driven through a stationary phase for separating compounds of a sample fluid comprised in the mobile phase, a flow rate of the mobile phase is controlled in dependence on a variation in a control value in the system.
