METHOD FOR ISOLATING TARGET NUCLEIC ACID USING HETERODUPLEX BINDING PROTEINS
Granted: November 21, 2024
Application Number:
20240384329
The invention includes methods and apparatus for separating mutations, especially rare and unknown mutations, using heteroduplex binding proteins. Nucleic acids may optionally be nicked at or near the mutation in order to promote heteroduplex binding protein recognition and binding. In particular, using the disclosed methods, it is possible to separate heteroduplexed nucleic acid strand pair from homoduplexed nucleic acid strand pairs having similar sequences and being at a much higher…
THIN FILM OPTICAL LENS AND METHOD FOR COATING A LENS
Granted: November 14, 2024
Application Number:
20240377555
A thin film optical lens and method for coating an optical substrate serves to apply alternating layers, with varying thicknesses, of a high index dielectric material and a low index dielectric material on first and second surfaces of an optical substrate. The high and low index dielectric materials are layered through thin film deposition. The low index dielectric material is SiO2. The high index dielectric material is ZrO2 and/or Indium Zinc Oxide. The spectral results from application…
Prism Harmonics
Granted: November 14, 2024
Application Number:
20240374885
This invention marks a significant innovation in the skincare and body care industry, being the first to harness methods for infusing skincare and body care products with a range of sound frequencies. While it prominently features the use of sound and solfeggio frequencies, the methodology is versatile, accommodating a broad spectrum of sound frequencies. Sound frequency infusion is an approach not replicated by any other entity in the market. This process, distinct from conventional…
CONTACT LAYER FOR LAYERED MATERIALS
Granted: November 7, 2024
Application Number:
20240373761
An electronics device comprises a substrate, a first layer of a first layered material arranged over the substrate, a second layer of a second layered material arranged over the substrate, an overlap region, and a contact layer. In the overlap region, the second layer is arranged over the first layer, and a section of a bottom surface of the second layer is parallel to a section of a top surface of the first layer. The contact layer comprises a plurality of electrically conductive lines…
MEDICAL IMAGE PROCESSING DEVICE, TREATMENT SYSTEM, MEDICAL IMAGE PROCESSING METHOD, AND STORAGE MEDIUM
Granted: November 7, 2024
Application Number:
20240369917
A medical image processing device according to an embodiment has a first image acquirer, a second image acquirer, a shifter, and a display controller. The first image acquirer acquires a first three-dimensional fluoroscopic image that is a three-dimensional fluoroscopic image of a patient captured in a patient treatment planning stage. The second image acquirer acquires a second three-dimensional fluoroscopic image that is a three-dimensional fluoroscopic image of the patient captured in…
INTEGRATED DEVICE WITH EXTERNAL LIGHT SOURCE FOR PROBING, DETECTING AND ANALYZING MOLECULES
Granted: November 7, 2024
Application Number:
20240369482
System and methods for analyzing single molecules and performing nucleic acid sequencing. An integrated device includes multiple pixels with sample wells configured to receive a sample, which when excited, emits radiation. The integrated device includes at least one waveguide configured to propagate excitation energy to the sample wells from a region of the integrated device configured to couple with an excitation energy source. A pixel may also include at least one element for directing…
MEDICAL IMAGE PROCESSING DEVICE, TREATMENT SYSTEM, MEDICAL IMAGE PROCESSING METHOD, AND STORAGE MEDIUM
Granted: October 31, 2024
Application Number:
20240362783
A medical image processing device according to an embodiment has a first image acquirer, a second image acquirer, a 3D-3D positioning executer, and a display controller. The first image acquirer acquires a first three-dimensional fluoroscopic image that is a three-dimensional fluoroscopic image of a patient. The second image acquirer acquires a second three-dimensional fluoroscopic image that is a three-dimensional fluoroscopic image of the patient. The 3D-3D positioning executer…
MEDICAL IMAGE PROCESSING DEVICE, TREATMENT SYSTEM, MEDICAL IMAGE PROCESSING METHOD, AND STORAGE MEDIUM
Granted: October 31, 2024
Application Number:
20240362782
According to an embodiment, a medical image processing device includes a first image acquirer, a second image acquirer, a treatment error acquirer, a difference calculator, and a differential statistical quantity calculator. The first image acquirer acquires a first fluoroscopic image of a patient. The second image acquirer acquires a second fluoroscopic image photographed at a timing different from the first fluoroscopic image. The treatment error acquirer acquires a treatment error…
QUANTUM STATE INFORMATION PROCESSING SYSTEM, QUANTUM MEASUREMENT AND CONTROL SYSTEM, AND QUANTUM COMPUTER
Granted: October 24, 2024
Application Number:
20240356532
Disclosed are a quantum state information processing system, a quantum measurement and control system, and a quantum computer. In this system, a sampling module is used to perform sampling processing on an analog signal collected from a qubit, a frequency mixing module is used to perform mixing processing on the sampled signal, a demodulation module is used to perform demodulation processing on a mixed signal, and a determining module is used to perform state classification on a…
FABRICATION METHOD FOR SUPERCONDUCTING CIRCUIT AND SUPERCONDUCTING QUANTUM CHIP
Granted: October 24, 2024
Application Number:
20240357945
Disclosed are a fabrication method for a superconducting circuit and a superconducting quantum chip. The fabrication method includes: determining, on a substrate, a first junction region located between a first electrical element and a second electrical element, and a second junction region located between a first conductive plate and a second conductive plate that are formed in advance; forming a Josephson junction in the second junction region; detect an electrical parameter of the…
Quantum Current Transformer Based on Bidirectional Light Compensation
Granted: October 24, 2024
Application Number:
20240356298
Provided is a quantum current transformer based on a bidirectional light compensation technology, including an annular cavity, a plurality of quantum probes, a front-end laser source, a back-end laser source, and a quantum processing system. The plurality of quantum probes are installed in the annular cavity and distributed in a circumference, the plurality of quantum probes are sequentially connected in series through an excitation optical fiber, and two quantum probes at both ends of a…
ROOM-TEMPERATURE AND AMBIENT-PRESSURE SUPERCONDUCTING CERAMIC AND METHODS FOR PRODUCING THE SAME
Granted: October 24, 2024
Application Number:
20240355500
Disclosed are a superconducting ceramic and methods for producing the same. The superconducting ceramic is represented by Formula 1, which is described in the specification. The methods are suitable for producing the superconducting ceramic. The superconducting ceramic exhibits superconductivity at room temperature and ambient pressure.
CLOCK GENERATION FOR A PHOTONIC QUANTUM COMPUTER
Granted: October 24, 2024
Application Number:
20240353734
A system for generating clock signals for a photonic quantum computing system includes a first pump photon source, a first photon-pair source optically coupled to the first pump photon source, and a first photodetector optically coupled to the first photon-pair source. The system also includes a first clock generator electrically coupled to the first photodetector, a second pump photon source, a second photon-pair source optically coupled to the second pump photon source, and a second…
SENSOR FOR LIFETIME PLUS SPECTRAL CHARACTERIZATION
Granted: October 24, 2024
Application Number:
20240353326
Some aspects relate to integrated devices for obtaining timing and/or spectral information from incident light. In some embodiments, a pixel may include one or more charge storage regions configured to receive charge carriers generated responsive to incident photons from a light source, with charge carriers stored in the charge storage region(s) indicative of spectral and timing information. In some embodiments, a pixel may include regions having different depths, each configured to…
ADVANCED QUANTUM PROCESSING SYSTEMS AND METHODS FOR PERFORMING QUANTUM LOGIC OPERATIONS
Granted: October 17, 2024
Application Number:
20240349626
Quantum processing element and method to perform logic operations on a quantum processing element are disclosed. The quantum processing element includes: a semiconductor, a dielectric material forming an interface with the semiconductor, a plurality of dopant dots embedded in the semiconductor, each of the dopant dots comprising one or more dopant atoms and one or more electrons or holes confined within the dopant dots, wherein spin of an unpaired electron or hole of each dopant dot…
Generation of Gottesman-Kitaev-Preskill (GKP) States Based on Multi-Peak Quantum States of Light
Granted: October 17, 2024
Application Number:
20240346357
A method includes receiving initial quantum states of light or a representation thereof at an optical circuit, from a set of sources. The initial quantum states of light include squeezed states of light, approximate squeezed cat states of light, and/or approximate states of light having at least 3 associated peaks. The optical circuit includes at least one programmable beamsplitter and at least one homodyne detector. The method also includes receiving, at the optical circuit, a signal to…
HERALDING-FREE CONNECTIONS IN QUANTUM COMPUTING
Granted: October 17, 2024
Application Number:
20240346354
Systems and methods for a quantum computing include a plurality of photonic processing stages, a plurality of heralding-free connections, and circuitry configured to regulate photon flow between adjacent stages such that decisions about stage settings or flow between adjacent stages are free of input from a previous stage. Each heralding-free connection is located between adjacent photonic processing stages. Each photonic processing stage includes at least two of an optical switch, a…
Managing Coupling of Optical Modes with Quantum State Emission Elements
Granted: October 17, 2024
Application Number:
20240345318
A method for interacting with quantum states over respective time intervals comprises: providing, from at least one optical fiber interface, a fiber-coupled optical mode that controls optical coupling to and/or from an optical fiber, where at least a portion of the optical fiber extends outside of an interior of a housing comprising the at least one optical fiber interface; providing a quantum state from each quantum state emission element (QSEE) housed on or inside the housing;…
METHODS OF SINGLE-CELL SEQUENCING
Granted: October 17, 2024
Application Number:
20240344122
Provided herein are methods of single-cell polypeptide and/or polynucleic acid sequencing, which facilitate the direct sequencing of a single cell without amplification. Also provided herein are compositions, kits and devices useful for the same.
SUPERCONDUCTING QUANTUM CIRCUIT AND FABRICATION METHOD THEREOF, QUANTUM COMPUTER
Granted: October 10, 2024
Application Number:
20240341202
A superconducting quantum circuit and a fabrication method thereof, as well as a quantum computer, belong to the field of quantum computing technology. The superconducting quantum circuit comprises a first superconducting element (21) and a second superconducting element (22) formed on a substrate (1), and a superconducting quantum interference device. The superconducting quantum interference device comprises: a bottom electrode (241) integrally connected to the second superconducting…
