Incorporating multiple targets in trajectory optimization for radiotherapy treatment planning
Granted: March 16, 2021
Patent Number:
10946216
Methods of treatment trajectory optimization for radiotherapy treatment of multiple targets include determining beam's eye view (BEV) regions and a BEV region connectivity manifold for each target group of a plurality of target groups separately. The information contained in the BEV regions and the BEV region connectivity manifolds for all target groups is used to guide an optimizer to find optimal treatment trajectories. To improve the visibility of insufficiently exposed voxels of…
Systems, methods, and devices for radiation beam alignment and radiation beam measurements using electronic portal imaging devices
Granted: March 9, 2021
Patent Number:
10940333
Systems and methods for using electronic portal imaging devices (EPIDs) as absolute radiation beam measuring devices and as radiation beam alignment devices without implementation of elaborate and complex calibration procedures.
Dosimetric projection of collimator geometry
Granted: March 9, 2021
Patent Number:
10940330
A method of calculating radiation dose includes dosimetric projection of a collimator geometry. The method includes defining a three-dimensional (3D) geometry of a collimating device which defines an aperture configured to allow a radiation beam passing through, projecting the collimating device along the radiation beam into a two-dimensional (2D) geometry in a plane, calculating dosimetric opacity values of the collimating device at locations adjacent to the aperture based on the 3D…
Systems and methods for three-dimensional visualization of deviation of volumetric structures with colored surface structures
Granted: February 23, 2021
Patent Number:
10930058
Embodiments of the present disclosure are directed to methods and computer systems for converting datasets into three-dimensional (“3D”) mesh surface visualization, displaying the mesh surface on a computer display, comparing two three-dimensional mesh surface structures by blending two primary different primary colors to create a secondary color, and computing the distance between two three-dimensional mesh surface structures converted from two closely-matched datasets. For…
Energy degrader having layer structure parallel to the incident beam direction for radiation therapy system
Granted: February 23, 2021
Patent Number:
10926103
An energy degrading device for attenuating energy of a particle beam with reduced emittance growth. An energy degrader comprises an emittance control material that can preferentially scatter the beam particles that is incident on a surface with a shallow angle. In one approach, the energy degrader may include alternating layers of a low-Z and a high-Z material, wherein the low Z material serves to attenuate energy of the beam particles by virtue of scattering and the high Z material…
Computation of radiating particle and wave distributions using a generalized discrete field constructed from representative ray sets
Granted: February 16, 2021
Patent Number:
10921756
The present system and method for simulating particles and waves is useful for calculations involving nuclear and full spectrum radiation transport, quantum particle transport, plasma transport and charged particle transport. The invention provides a mechanism for creating accurate invariants for embedding in general three-dimensional problems and describes means by which a series of simple single collision interaction finite elements can be extended to formulate a complex…
Flash therapy treatment planning and oncology information system having dose rate prescription and dose rate mapping
Granted: February 16, 2021
Patent Number:
10918886
A computing system comprising a central processing unit (CPU), and memory coupled to the CPU and having stored therein instructions that, when executed by the computing system, cause the computing system to execute operations to generate a radiation treatment plan. The operations include accessing a minimum prescribed dose to be delivered into and across the target, determining a number of beams and directions of the beams, and determining a beam energy for each of the beams, wherein the…
Systems, methods and devices for automated target volume generation
Granted: February 16, 2021
Patent Number:
10918885
Systems and method for automatically generating structures, such as target volumes, in a treatment image using structure-guided deformation to propagate the structures from a planning image onto the subsequently acquired treatment image.
Systems, methods, and devices for high-energy irradiation
Granted: February 9, 2021
Patent Number:
10912952
A high-energy radiation treatment system can comprise a laser-driven accelerator system, a patient monitoring system, and a control system. The laser-driven accelerator system, such as a laser-driven plasma accelerator or a laser-driven dielectric microstructure accelerator, can be constructed to irradiate a patient disposed on a patient support. The patient monitoring system can be configured to detect and track a location or movement of a treatment volume within the patient. The…
Adaptive pencil beam scanning
Granted: February 9, 2021
Patent Number:
10912953
Embodiments of the present invention disclose methods and systems for producing an adaptive pencil beam having an adjustable lateral beam size and Bragg-peak width. According to one disclosed embodiment, an apparatus for producing an adaptive pencil beam is disclosed. The apparatus includes a set of momentum band expanders configured to widen a momentum spread of a pencil beam, where a momentum band expander is selected from the set of momentum band expanders to receive the pencil beam,…
Method and apparatus pertaining to radiation-treatment plan optimization
Granted: February 9, 2021
Patent Number:
10912951
A radiation-treatment plan that comprises a plurality of dose-delivery fractions can be optimized by using fraction dose objectives and at least one other, different dose objective. This use of fraction dose objectives can comprise accumulating doses delivered in previous dose-delivery fractions. The other, different dose objective can comprise a remaining total dose objective, a predictive dose objective, or some other dose objective of choice. An existing radiation-treatment plan…
Multi-criteria optimization tools including time-based criteria for radiation therapy
Granted: February 9, 2021
Patent Number:
10912949
Multi-criteria optimization of radiation therapy tools for receiving a plurality of criteria including one or more sets of competing objectives. The competing objective can include delivery time criteria, fractionation criteria or similar time-based criteria. One or more radiation therapy plans can be determined based on a multi-criteria optimization of the plurality of criteria for the radiation therapy treatment. The one or more optimized radiation therapy plans can be output for…
Radiation anode target systems and methods
Granted: February 2, 2021
Patent Number:
10910188
Presented systems and methods facilitate efficient and effective generation and delivery of radiation. A radiation generation system can comprise: a particle beam gun, a high energy dissipation anode target (HEDAT); and a liquid anode control component. In some embodiments, the particle beam gun generates an electron beam. The HEDAT includes a solid anode portion (HEDAT-SAP) and a liquid anode portion (HEDAT-LAP) that are configured to receive the electron beam, absorb energy from the…
Triggered treatment systems and methods
Granted: January 26, 2021
Patent Number:
10898730
In various embodiments, a radiation therapy method can include loading a planning image of a target in a human. In addition, the position of the target can be monitored. A computation can be made of an occurrence of substantial alignment between the position of the target and the target of the planning image. Furthermore, after the computing, a beam of radiation is triggered to deliver a dosage to the target in a short period of time (e.g., less than a second).
Phantom setup and source-to-surface distance verification using radiation imaging
Granted: January 26, 2021
Patent Number:
10898158
A phantom setup and source-to-surface distance (SSD) verification method uses radiation images. In an exemplary method, a phantom is positioned on a support relative to a radiation source such that a surface of the phantom is horizontally leveled at or approximate to a desired value of SSD. The radiation source is then positioned at a gantry angle predetermined at least based on the desired value of SSD such that a ray of radiation from the radiation source aligns with a horizontal…
Multileaf collimator with alternating trapezoidal leaf geometry design
Granted: January 12, 2021
Patent Number:
10888713
A multileaf collimator includes a plurality of beam-blocking leaves of a first type and a plurality of beam-blocking leaves of a second type. The beam-blocking leaves of the first type are alternatingly arranged with the beam-blocking leaves of the second type side by side. Each of the beam-blocking leaves of the first type has a trapezoidal geometry viewed in the leaf longitudinal moving direction comprising a wider end and a narrower end with the wider end being proximal to a source.…
Dynamic patient positioning system
Granted: January 5, 2021
Patent Number:
10881878
A system includes a first radiation source configured to provide therapeutic radiation in a treatment area and an automated patient transport configured to transport a patient from a preparation area to the treatment area, to position a treatment volume in the patient relative to the therapeutic radiation from the first radiation source, and to support the patient in receiving the therapeutic radiation. The automated patient transport comprises a first detector configured to detect a…
Beam position monitors for medical radiation machines
Granted: December 29, 2020
Patent Number:
10879028
An apparatus includes: a structure having a lumen for accommodating a beam (e.g., electron beam, proton beam, or a charged particle beam), wherein the structure is a component of a medical radiation machine having a target for interaction with the beam to generate radiation; and a first beam position monitor comprising a first electrode and a second electrode, the first electrode being mounted to a first side of the structure, the second electrode being mounted to a second side of the…
Non-achromatic compact gantry
Granted: December 15, 2020
Patent Number:
10864384
Embodiments of the present invention provide a compact gantry designed to provide particle therapy using a particle beam. A gantry for providing the particle therapy comprises a first dipole magnet operable to bend a particle beam received from a cyclotron by a first degree amount. The gantry further comprises a plurality of quadrupole magnets configured to condition the beam asymmetrically to produce an asymmetric beam, wherein a configuration of the quadrupole magnets is determined…
System and method for in-layer synchronization for fast spot rescanning
Granted: December 8, 2020
Patent Number:
10857392
To overcome the difficulties inherent in conventional proton therapy systems, new techniques are described herein for synchronizing the application of proton radiation with the periodic movement of a target area. In an embodiment, a method is provided that combines multiple rescans of a spot scanning proton beam while monitoring the periodic motion of the target area, and aligning the applications of the proton beam with parameters of the periodic motion. For example, the direction(s)…
