Interlaced multi-energy betatron with adjustable pulse repetition frequency
Granted: May 10, 2016
Patent Number:
9338875
Variable pulse frequency during an output session of a betatron device and adjustable energy from pulse to pulse are provided. A different bias magnetic field may be used for different cycles of an output session, thereby providing different pulse energies. In one example, the bias field can be switched from a positive value to zero, with energy stored in a storage device when the bias field is zero. The bias field can also be used to expand electrons from a stable orbit when the bias…
Methods and systems for estimating scatter
Granted: May 3, 2016
Patent Number:
9330458
Techniques described herein generally relate to estimating scatter. In one embodiment, one example method for estimating scatter associated with a target object may include generating a set of original projections associated with the target object, generating a set of reference scatter data associated with the target object at one or more selected projection angles, generating a first set of estimated scatter data associated with the target object also at the one or more selected…
Radiation therapy treatment plan improvement through use of knowledge base
Granted: May 3, 2016
Patent Number:
9327139
A method for determining a radiation therapy dose distribution starts with selecting and downloading a treatment type from a database. Then an organ at risk (OAR) distance to target map is determined, wherein the OAR distance to target map comprises distances to a target organ for respective portions of at least one OAR, and wherein the OAR distances are determined from at least one segmented patient organ image. Now a cohort average dose distance to target histogram is selected and…
Patient positioning and support systems
Granted: May 3, 2016
Patent Number:
9326907
A patient positioning system employs an arm having a first portion and a second portion which is telescopic relative to the first portion. A first positioning device may be coupled to the first portion of the arm providing support for the arm. The first positioning device is rotatable on a first axis, allowing the arm to rotate with the first positioning device. The second positioning device is coupled to the second portion of the arm and movable with the second portion of the arm…
Dual-energy X-ray tubes
Granted: April 26, 2016
Patent Number:
9324536
Dual-energy x-ray tubes. In one example embodiment, a dual-energy x-ray tube includes an evacuated enclosure, an anode positioned within the evacuated enclosure, a first cathode positioned within the evacuated enclosure, and a second cathode positioned within the evacuated enclosure. The first cathode and the second cathode are configured to operate simultaneously at different voltages.
Multileaf collimators with transverse motion
Granted: April 26, 2016
Patent Number:
9324468
A collimation assembly includes a multileaf collimator and motion assembly. The multileaf collimator includes a support body and a plurality of pairs of beam blocking leaves supported by the support body. The beam blocking leaves are longitudinally movable in a first direction. The motion assembly includes an actuator and a guide assembly operable to move the support body and thereby allowing the plurality of pairs of beam blocking leaves to move in a second direction generally…
Image processing of images that include marker images
Granted: April 26, 2016
Patent Number:
9324152
A method, includes: obtaining an image, the image having marker images and a background image; identifying presence of an object in the background image using a processor; and providing a signal for stopping a procedure if the presence of the object is identified. An image processing apparatus, includes: a processor configured for: obtaining an image, the image having marker images and a background image; identifying presence of an object in the background image; and providing a signal…
Systems and methods for real-time target validation for image-guided radiation therapy
Granted: April 19, 2016
Patent Number:
9314160
Systems and methods for real-time target validation during radiation treatment therapy based on real-time target displacement and radiation dosimetry measurements.
Constructive anatomic geometry
Granted: April 19, 2016
Patent Number:
9317969
A method involving an image of an anatomy, includes: obtaining an image of an anatomy; obtaining a program instruction from a user for creating an object in the image; and executing the program instruction to create the object in the image, wherein the act of executing the program instruction is performed using a processor. A computer product having a non-transitory medium storing a set of instructions, an execution of which causes a method to be performed, the method includes: obtaining…
Preparative regimen for engraftment, growth and differentiation of non-hematopoeitic cells in vivo after transplantation
Granted: April 19, 2016
Patent Number:
9314486
Disclosed are methods of obtaining an expanded population of mammalian ex vivo cells for treating a mammalian subject by (a) administering to a subject an effective amount of an agent that confers a growth disadvantage to at least a subset of endogenous cells at the site of engraftment; (b) administering to the subject an effective amount of a mitogenic stimulus for the ex vivo cells; and (c) administering the ex vivo cells to the subject, wherein the ex vivo cells engraft at the site…
Radiation systems with minimal or no shielding requirement on building
Granted: April 12, 2016
Patent Number:
9308395
A radiation system includes a support, a capsule rotatably coupled to the support, a radiation source movably coupled to the capsule, wherein the radiation source is configured to provide a treatment radiation beam, and is capable of being turned on or off in response to a control signal, and a collimator located next to the radiation source, wherein the capsule defines a space for accommodating a portion of a patient, and includes a shielding material for attenuating radiation resulted…
Methods for image processing
Granted: March 29, 2016
Patent Number:
9299143
An image processing method includes: obtaining an image that includes a ball image and a cone image; obtaining an estimate of a center of the ball image; converting the image to a converted image using a processor based at least in part on the estimate of the center of the ball image, wherein the converted image comprises a converted ball image that looks different from the ball image in the image, and a converted cone image that looks different from the cone image in the image;…
System and method for estimating and manipulating estimated radiation dose
Granted: March 22, 2016
Patent Number:
9289627
Methods are provided for permitting manipulation of an achievable dose distribution estimate deliverable by a radiation delivery apparatus for proposed treatment of a subject. One such method comprises: determining a dose modification voxel for which it is desired to modify the dose value and a corresponding magnitude of desired dose modification; for each of a plurality of beams: (i) characterizing the beam as a two-dimensional array of beamlets, wherein each beamlet is associated with…
Compact proton therapy system with energy selection onboard a rotatable gantry
Granted: March 15, 2016
Patent Number:
9283407
Systems and apparatuses for providing particle beams for radiation therapy with a compact design and suitable to a single treatment room. The radiation system comprises a stationary cyclotron coupled to a rotating gantry assembly through a beam line assembly. The system is equipped with a single set of dipole magnets that are installed on the rotating gantry assembly and undertakes the dual functions of beam energy selection and beam deflection. The energy degrader may be exposed to the…
Apparatus and methods for implanting objects, such as bronchoscopically implanting markers in the lung of patients
Granted: March 15, 2016
Patent Number:
9283053
Apparatuses and methods for implanting objects, such as a marker, in the lungs of patients. In one embodiment, a bronchoscopic catheter assembly for implanting an object in the lung of a patient includes a handle, a delivery catheter projecting outwardly from the handle, and a push wire contained within the catheter In one aspect of this embodiment, the catheter can be configured to releasably hold a plurality of markers at a distal end. In another aspect of this embodiment, the push…
Liquid metal containment in an X-ray tube
Granted: March 1, 2016
Patent Number:
9275822
Liquid metal containment in an x-ray tube. In one example embodiment, an x-ray tube anode assembly includes a shaft terminated by a head and an anode connected to an anode hub. The anode hub is at least partially surrounding the head of the shaft. The anode hub is configured to contain a volume of a liquid metal and to rotate around the stationary shaft. The anode hub may also define a catch space within the anode hub that is configured to catch the liquid metal in order to contain the…
System and method for triggering an imaging process based on non-periodicity in breathing
Granted: March 1, 2016
Patent Number:
9271692
A method of triggering an imaging process includes obtaining breathing signals, analyzing the breathing signals to identify a non-periodicity in a subject's breathing, and generating a signal to cause an imaging process to begin in response to the identified non-periodicity. A computer product having a set of instructions stored in a non-transitory medium, wherein an execution of the instructions causes a method to be performed, the method includes obtaining breathing signals, analyzing…
NIR image-guided targeting
Granted: March 1, 2016
Patent Number:
9271673
A method for targeting. The method includes determining skin characteristics in a region of a patient. An in-treatment optical scan is performed on a region of a patient, wherein the in-treatment optical scan comprises a near infrared (NIR) energy source. A plurality of detected signals is detected from the optical scan. The skin characteristics are filtered out from the plurality of detected signals. Skeletal anatomy positioning associated with the region is determined from the…
Systems, methods, and devices for real-time treatment verification using an electronic portal imaging device
Granted: February 23, 2016
Patent Number:
9265971
A radiation dose received by a patient from a radiation therapy system can be verified by acquiring a cine stream of image frames from an electronic portal imaging device (EPID) that is arranged to detect radiation exiting the patient during irradiation. The cine stream of EPID image frames can be processed in real-time to form exit images providing absolute dose measurements at the EPID (dose-to-water values), which is representative of the characteristics of the radiation received by…
Universal kV-MV imagers
Granted: February 23, 2016
Patent Number:
9268037
An x-ray imaging device may include a detector array and an x-ray converting layer coupled to the detector array. The detector array and the x-ray converting layer may be configured such that x-rays traverse the detector array before propagating in the x-ray converting layer. The x-ray imaging device may also include a buildup layer behind the x-ray converting layer. The x-ray imaging device may be used as a “universal” imager for both MV and kV imaging.
