Flash therapy treatment planning and oncology information system having dose rate prescription and dose rate mapping
Granted: January 9, 2024
Patent Number:
11865364
A computing system comprising a central processing unit (CPU), and memory coupled to the CPU and having stored therein instructions that, when executed by the computing system, cause the computing system to execute operations to generate a radiation treatment plan. The operations include accessing a minimum prescribed dose to be delivered into and across the target, determining a number of beams and directions of the beams, and determining a beam energy for each of the beams, wherein the…
System and method for scanning pattern optimization for flash therapy treatment planning
Granted: January 9, 2024
Patent Number:
11865361
Embodiments of the present invention provide methods and systems for proton therapy planning that maximize the dose rate for different target sizes for FLASH therapy treatment are disclosed herein according to embodiments of the present invention. According to embodiments, non-standard scanning patterns can be generated, for example, using a TPS optimizer, to maximize dose rate and the overall FLASH effect for specific volumes at risk. The novel scanning patterns can include scanning…
Increased beam output and dynamic field shaping for radiotherapy system
Granted: January 2, 2024
Patent Number:
11857805
Systems and methods provide a radiotherapy treatment by focusing an electron beam on an x-ray target (e.g., a tungsten plate) to produce a high-yield x-ray output with improved field shaping. A modified electron beam spatial distribution is employed to scan the x-ray target, such as a 2D periodic beam path, which advantageously lowers the temperature of the x-ray target compared to typical compact beam spatial distribution. As a result, the x-ray target can produce a high yield x-ray…
Radiation anode target systems and methods
Granted: December 26, 2023
Patent Number:
11854761
Presented systems and methods facilitate efficient and effective generation and delivery of radiation. A radiation generation system can comprise: a particle beam gun, a high energy dissipation anode target (HEDAT); and a liquid anode control component. In some embodiments, the particle beam gun generates an electron beam. The HEDAT includes a solid anode portion (HEDAT-SAP) and a liquid anode portion (HEDAT-LAP) that are configured to receive the electron beam, absorb energy from the…
NIR image-guided targeting
Granted: December 26, 2023
Patent Number:
11850022
A method includes determining skin characteristics in a region of a patient. An in-treatment optical scan is performed on a region of a patient, wherein the in-treatment optical scan comprises a near infrared (NIR) energy source. A plurality of detected signals is detected from the optical scan. The skin characteristics are filtered out from the plurality of detected signals. Skeletal anatomy positioning associated with the region is determined from the plurality of signals that is…
Cryogenic system and methods
Granted: December 26, 2023
Patent Number:
11849989
Embodiments of the present invention relate to cryogenic systems and methods useful to cool objects, including living tissue, to freezing or cryogenic temperatures by placing the object in thermal communication with sub-cooled supercritical nitrogen.
Radiotherapy methods, systems, and workflow-oriented graphical user interfaces
Granted: December 19, 2023
Patent Number:
11844962
Disclosed herein are radiotherapy methods and systems that can display a workflow-oriented graphical user interface(s). In an embodiment, a method comprises presenting, by a server, a first page of a first graphical user interface on the radiotherapy console associated with a radiotherapy machine in a treatment room, wherein the first graphical user interface contains a plurality of pages, each page corresponding to a stage of treatment implemented by the radiotherapy machine, and the…
Blood-tissue surface based radiosurgical renal treatment planning
Granted: December 19, 2023
Patent Number:
11844959
Devices, systems, and methods for planning radiosurgical treatments for neuromodulating a portion of the renovascular system may be used to plan radiosurgical neuromodulation treatments for conditions or disease associated with elevated central sympathetic drive. The renal nerves may be located and targeted at the level of the ganglion and/or at postganglionic positions, as well as preganglionic positions. Target regions include the renal plexus, celiac ganglion, the superior mesenteric…
Systems and methods for real-time target validation for image-guided radiation therapy
Granted: November 21, 2023
Patent Number:
11819308
Systems and methods for real-time target validation during radiation treatment therapy based on real-time target displacement and radiation dosimetry measurements.
Radiotherapy methods, systems, and workflow-oriented graphical user interfaces
Granted: November 14, 2023
Patent Number:
11817210
Disclosed herein are radiotherapy methods and systems that can display a workflow-oriented graphical user interface(s). In an embodiment, a method comprises retrieving, by a server, information from a radiotherapy file associated with a patient, the information comprising an alignment data of at least a treatment region of the patient; presenting, by the server, for display on a graphical user interface, an image corresponding to the patient positioned on a couch of a radiotherapy…
Brachytherapy applicator formation method and apparatus
Granted: November 14, 2023
Patent Number:
11817199
A brachytherapy applicator is formed to use when administering therapeutic radiation to a particular patient's targeted area via brachytherapy. This process accesses image information for a patient that includes the targeted area and at least some adjacent non-targeted area. A control circuit uses that image information with prescribed dosing information for that patient to automatically generate a brachytherapy applicator design specifically to treat the particular patient's targeted…
Variable cryosurgical probe planning system
Granted: November 14, 2023
Patent Number:
11813013
A cryosurgical system including a computer system programmed with software configured to perform the following steps: a) capturing at least one first view of a region of interest in a human body; b) capturing at least one second view of the region of interest; c) outlining the region of interest and at least one area outside the region of interest with the assistance of an operator; d) constructing a 3-dimensional model of the region of interest and the at least one area outside the…
Radiotherapy methods, systems, and workflow-oriented graphical user interfaces
Granted: October 17, 2023
Patent Number:
11786756
Disclosed herein are radiotherapy methods and systems that can display a workflow-oriented graphical user interface(s). In an embodiment, a method comprises presenting, by a server, a graphical user interface for display on a screen positioned on a gantry of a radiotherapy machine, wherein the graphical user interface comprises a page corresponding to a radiotherapy treatment of a patient, wherein the page comprises a first graphical element indicating at least one attribute of alignment…
Systems, methods, and devices for real-time treatment verification using an electronic portal imaging device
Granted: October 17, 2023
Patent Number:
11786758
A radiation dose received by a patient from a radiation therapy system can be verified by acquiring a cine stream of image frames from an electronic portal imaging device (EPID) that is arranged to detect radiation exiting the patient during irradiation. The cine stream of EPID image frames can be processed in real-time to form exit images providing absolute dose measurements at the EPID (dose-to-water values), which is representative of the characteristics of the radiation received by…
Radiotherapy methods, systems, and workflow-oriented graphical user interfaces
Granted: October 17, 2023
Patent Number:
11786757
Disclosed herein are radiotherapy methods and systems that can display a workflow-oriented graphical user interface(s). In an embodiment, a method comprises presenting, by a server, a graphical user interface for display on a screen positioned on a gantry of a radiotherapy machine, wherein the graphical user interface comprises a page corresponding to a radiotherapy treatment of a patient, wherein the page comprises a first graphical element indicating at least one attribute of alignment…
Method and system for remote monitoring of proton beam emitting and delivery systems
Granted: October 10, 2023
Patent Number:
11785702
A remote diagnostic monitoring of operating states for physical components of a particle accelerator system includes generating, by at least one processor, a component hierarchy corresponding to a physical arrangement of one or more physical components of a particle emitting system and including corresponding operating indicators of operating states of the physical components, identifying, by the at least one processor, a faulted physical component among the physical components,…
Magnetoresistive linear position detection in a radiation therapy system
Granted: October 3, 2023
Patent Number:
11771924
A multileaf collimator includes a plurality of movable leaves for shaping a radiotherapy beam, wherein each leaf is independently movable in a same linear travel direction. Each leaf includes a linear array of magnets disposed on a measurement surface of the leaf and an array of magnetoresistive sensors that is disposed proximate the measurement surfaces of the leaves.
Methods of use of ultra-high dose rate radiation and therapeutic agent
Granted: October 3, 2023
Patent Number:
11771920
Methods for treating tumors by administering FLASH radiation and a therapeutic agent to a patient with cancer are disclosed. The methods provide the dual benefits of anti-tumor efficacy plus normal tissue protection when combining therapeutic agents with FLASH radiation to treat cancer patients. The methods described herein also allow for the classification of patients into groups for receiving optimized radiation treatment in combination with a therapeutic agent based on…
Systems, methods, and devices for multi-energy x-ray imaging
Granted: October 3, 2023
Patent Number:
11771388
A system can have an x-ray source that generates a series of individual x-ray pulses for multi-energy imaging. A first x-ray pulse can have a first energy level and a subsequent second x-ray pulse in the series can have a second energy level different from the first energy level. An x-ray imager can receive the x-rays from the x-ray source and can detect the received x-rays for image generation. A generator interface box (GIB) controls the x-ray source to provide the series of individual…
Quality assurance process for radiation therapy treatment planning
Granted: September 26, 2023
Patent Number:
11766575
A method enables testing and evaluation of an expert human reviewer or an artificial intelligence (AI) error detection engine associated with a radiotherapy treatment planning process. Intentional errors are introduced into the output of a software module or AI engine that performs a certain step in the radiotherapy treatment planning process. The efficacy of the human or AI reviewer in detecting errors can then be evaluated or tested by determining whether the human or AI reviewer has…
