Single-pass imaging and radiation treatment delivery via an extended rotation gantry
Granted: February 21, 2023
Patent Number:
11583704
An example method of radiation therapy in a radiation therapy system that includes a gantry with a treatment-delivering X-ray source and an imaging X-ray source mounted thereon is described. The method includes rotating the gantry in a first direction at a first rotational velocity about an open bore and concurrently rotating an annular support structure at a second rotational velocity about the open bore, wherein the second rotational velocity is less than the first rotational velocity.…
Radiotherapy methods, systems, and workflow-oriented graphical user interfaces
Granted: February 14, 2023
Patent Number:
11577095
Disclosed herein are radiotherapy methods and systems that can display a workflow-oriented graphical user interface(s). A method comprises presenting a plurality of pages for display, each corresponding to a stage of a radiotherapy treatment for a patient; in response to receiving an indication that a surface of a patient is aligned, retrieving, from a radiotherapy file, a first image of an internal target aligned in accordance with treatment attributes; receiving a second image of the…
Isochronous cyclotrons employing magnetic field concentrating or guiding sectors
Granted: January 31, 2023
Patent Number:
11570880
An isochronous cyclotron including one or more coils and a plurality of pairs of bulk superconductor sectors. The one or more coils can be configured to generate a magnetic field in the beam chamber having a magnetic flux density that increases radially from the central axis of the beam chamber, and is orientated substantially perpendicular to the median acceleration plane of the beam chamber. Each pair of bulk superconductor sectors can be disposed on opposite sides of the median…
Knowledge based multi-criteria optimization for radiotherapy treatment planning
Granted: January 31, 2023
Patent Number:
11565126
A method of generating a treatment plan for treating a patient with radiotherapy, the method includes obtaining a plurality of sample plans, which are generated by use of a knowledge base comprising historical treatment plans and patient data. The method also includes performing a multi-criteria optimization based on the plurality of sample plans to construct a Pareto frontier, where the plurality of sample plans are evaluated with at least two objectives measuring qualities of the…
Systems and methods for pseudo image data augmentation for training machine learning models
Granted: January 24, 2023
Patent Number:
11562482
Systems and methods for augmenting a training data set with annotated pseudo images for training machine learning models. The pseudo images are generated from corresponding images of the training data set and provide a realistic model of the interaction of image generating signals with the patient, while also providing a realistic patient model. The pseudo images are of a target imaging modality, which is different than the imaging modality of the training data set, and are generated…
Method and apparatus to facilitate administering therapeutic radiation to a heterogeneous body
Granted: January 24, 2023
Patent Number:
11559701
These teachings facilitate the administration of therapeutic radiation to a heterogeneous patient volume using a radiation beam source. More particularly, these teachings provide for determining a cross-sectional size of a radiation beam as corresponds to that radiation beam source and also for determining density information corresponding to the aforementioned heterogeneous body. These teachings then provide for generating a three-dimensional radiation dose calculation for the…
Systems and methods for pseudo image data augmentation for training machine learning models
Granted: January 24, 2023
Patent Number:
11562482
Systems and methods for augmenting a training data set with annotated pseudo images for training machine learning models. The pseudo images are generated from corresponding images of the training data set and provide a realistic model of the interaction of image generating signals with the patient, while also providing a realistic patient model. The pseudo images are of a target imaging modality, which is different than the imaging modality of the training data set, and are generated…
Method and apparatus to facilitate administering therapeutic radiation to a heterogeneous body
Granted: January 24, 2023
Patent Number:
11559701
These teachings facilitate the administration of therapeutic radiation to a heterogeneous patient volume using a radiation beam source. More particularly, these teachings provide for determining a cross-sectional size of a radiation beam as corresponds to that radiation beam source and also for determining density information corresponding to the aforementioned heterogeneous body. These teachings then provide for generating a three-dimensional radiation dose calculation for the…
Flash therapy treatment planning and oncology information system having dose rate prescription and dose rate mapping
Granted: January 17, 2023
Patent Number:
11554271
A computing system comprising a central processing unit (CPU), and memory coupled to the CPU and having stored therein instructions that, when executed by the computing system, cause the computing system to execute operations to generate a radiation treatment plan. The operations include accessing a minimum prescribed dose to be delivered into and across the target, determining a number of beams and directions of the beams, and determining a beam energy for each of the beams, wherein the…
Systems, methods, and devices for high-energy irradiation
Granted: January 10, 2023
Patent Number:
11547873
A high-energy radiation treatment system can comprise a laser-driven accelerator system, a patient monitoring system, and a control system. The laser-driven accelerator system, such as a laser-driven plasma accelerator or a laser-driven dielectric microstructure accelerator, can be constructed to irradiate a patient disposed on a patient support. The patient monitoring system can be configured to detect and track a location or movement of a treatment volume within the patient. The…
Display screen of an electronic device with a graphical user interface
Granted: January 10, 2023
Patent Number:
D975112
Defining dose rate for pencil beam scanning
Granted: January 3, 2023
Patent Number:
11541252
The dose rate of voxels within a particle beam (e.g., proton beam) treatment field delivered using pencil beam scanning (PBS) is calculated, and a representative dose rate for the particle beam treatment field is reported. The calculations account for a dose accumulation in a local region or a sub-volume (e.g., a voxel) as a function of time.
Generating and applying robust dose prediction models
Granted: December 27, 2022
Patent Number:
11537912
Nominal values of parameters, and perturbations of the nominal values, that are associated with previously defined radiation treatment plans are accessed. For each treatment field of the treatment plans, a field-specific planning target volume (fsPTV) is determined based on those perturbations. At least one clinical target volume (CTV) and at least one organ-at-risk (OAR) volume are also delineated. Each OAR includes at least one sub-volume that is delineated based on spatial…
Asymmetric dual-mode ionization systems and methods
Granted: December 27, 2022
Patent Number:
11534626
An asymmetric dual-mode ionization chamber measurement system can include a first high-voltage plate, a second high-voltage plate and a readout plate. The first high-voltage plate can be disposed from the readout plate by a first active volume. The second high-voltage plate can be disposed from the readout plate by a second active volume. A high-voltage potential can be coupled to the first high-voltage plate during a first mode, and to the second high-voltage plate during a second mode.…
Radiation treatment based on dose rate
Granted: December 27, 2022
Patent Number:
11534625
A dose rate-volume histogram can be generated for a target volume. The dose rate-volume histogram can be stored in computer system memory and used to generate a radiation treatment plan. The radiation treatment plan can be used as the basis for treating a patient using a radiation treatment system.
Systems and methods for three-dimensional visualization of deviation of volumetric structures with colored surface structures
Granted: December 20, 2022
Patent Number:
11532119
Embodiments of the present disclosure are directed to methods and computer systems for converting datasets into three-dimensional (“3D”) mesh surface visualization, displaying the mesh surface on a computer display, comparing two three-dimensional mesh surface structures by blending two primary different primary colors to create a secondary color, and computing the distance between two three-dimensional mesh surface structures converted from two closely-matched datasets. For…
Radiation therapy systems and methods
Granted: December 20, 2022
Patent Number:
11529532
A radiation therapy system includes an accelerator and beam transport system that generates a beam of particles. The accelerator and beam transport system guides the beam on a path and into a nozzle that is operable for aiming the beam toward an object. The nozzle includes a scanning magnet operable for steering the beam toward different locations within the object, and also includes a beam energy adjuster configured to adjust the beam by, for example, placing different thicknesses of…
Radiotherapy methods, systems, and workflow-oriented graphical user interfaces
Granted: December 6, 2022
Patent Number:
11517771
Disclosed herein are radiotherapy systems and methods that can display a workflow-oriented graphical user interface(s). In an embodiment, a system comprises a radiotherapy machine comprising: a couch; and a gantry having a camera in communication with a server, wherein the server is configured to: present for display, in real time on a screen associated with the radiotherapy machine, images received from the camera, wherein when the gantry changes its orientation, the camera revises at…
Automatically-planned radiation-based treatment
Granted: October 25, 2022
Patent Number:
11478660
Deep learning approaches automatically segment at least some breast tissue images while non-deep learning approaches automatically segment organs-at-risk. Both three-dimensional CT imaging information and two-dimensional orthogonal topogram imaging information can be used to determine virtual-skin volume. The foregoing imaging information can also serve to automatically determine a body outline for at least a portion of the patient. That body outline, along with the virtual-skin volume…
Trajectory optimization using dose estimation and conflict detection
Granted: October 25, 2022
Patent Number:
11478661
Systems and methods for radiation treatment planning can include a computing system determining an estimate of a radiation dose distribution within an anatomical region of a patient, and determining a cost matrix representing an objective function, using the estimate of the radiation dose distribution. The computing system can project the cost matrix on each of a plurality of fluence planes. Each of the plurality of fluence planes can be associated with a corresponding gantry-couch…
