Systems, methods, and devices for high-energy irradiation
Granted: January 10, 2023
Patent Number:
11547873
A high-energy radiation treatment system can comprise a laser-driven accelerator system, a patient monitoring system, and a control system. The laser-driven accelerator system, such as a laser-driven plasma accelerator or a laser-driven dielectric microstructure accelerator, can be constructed to irradiate a patient disposed on a patient support. The patient monitoring system can be configured to detect and track a location or movement of a treatment volume within the patient. The…
Display screen of an electronic device with a graphical user interface
Granted: January 10, 2023
Patent Number:
D975112
Defining dose rate for pencil beam scanning
Granted: January 3, 2023
Patent Number:
11541252
The dose rate of voxels within a particle beam (e.g., proton beam) treatment field delivered using pencil beam scanning (PBS) is calculated, and a representative dose rate for the particle beam treatment field is reported. The calculations account for a dose accumulation in a local region or a sub-volume (e.g., a voxel) as a function of time.
Generating and applying robust dose prediction models
Granted: December 27, 2022
Patent Number:
11537912
Nominal values of parameters, and perturbations of the nominal values, that are associated with previously defined radiation treatment plans are accessed. For each treatment field of the treatment plans, a field-specific planning target volume (fsPTV) is determined based on those perturbations. At least one clinical target volume (CTV) and at least one organ-at-risk (OAR) volume are also delineated. Each OAR includes at least one sub-volume that is delineated based on spatial…
Asymmetric dual-mode ionization systems and methods
Granted: December 27, 2022
Patent Number:
11534626
An asymmetric dual-mode ionization chamber measurement system can include a first high-voltage plate, a second high-voltage plate and a readout plate. The first high-voltage plate can be disposed from the readout plate by a first active volume. The second high-voltage plate can be disposed from the readout plate by a second active volume. A high-voltage potential can be coupled to the first high-voltage plate during a first mode, and to the second high-voltage plate during a second mode.…
Radiation treatment based on dose rate
Granted: December 27, 2022
Patent Number:
11534625
A dose rate-volume histogram can be generated for a target volume. The dose rate-volume histogram can be stored in computer system memory and used to generate a radiation treatment plan. The radiation treatment plan can be used as the basis for treating a patient using a radiation treatment system.
Systems and methods for three-dimensional visualization of deviation of volumetric structures with colored surface structures
Granted: December 20, 2022
Patent Number:
11532119
Embodiments of the present disclosure are directed to methods and computer systems for converting datasets into three-dimensional (“3D”) mesh surface visualization, displaying the mesh surface on a computer display, comparing two three-dimensional mesh surface structures by blending two primary different primary colors to create a secondary color, and computing the distance between two three-dimensional mesh surface structures converted from two closely-matched datasets. For…
Radiation therapy systems and methods
Granted: December 20, 2022
Patent Number:
11529532
A radiation therapy system includes an accelerator and beam transport system that generates a beam of particles. The accelerator and beam transport system guides the beam on a path and into a nozzle that is operable for aiming the beam toward an object. The nozzle includes a scanning magnet operable for steering the beam toward different locations within the object, and also includes a beam energy adjuster configured to adjust the beam by, for example, placing different thicknesses of…
Radiotherapy methods, systems, and workflow-oriented graphical user interfaces
Granted: December 6, 2022
Patent Number:
11517771
Disclosed herein are radiotherapy systems and methods that can display a workflow-oriented graphical user interface(s). In an embodiment, a system comprises a radiotherapy machine comprising: a couch; and a gantry having a camera in communication with a server, wherein the server is configured to: present for display, in real time on a screen associated with the radiotherapy machine, images received from the camera, wherein when the gantry changes its orientation, the camera revises at…
Radiation therapy knowledge exchange
Granted: October 25, 2022
Patent Number:
11481728
A method for implementing a radiation therapy knowledge exchange starts with searching a database of cases studies and selecting a case study. The selected case study is downloaded. The downloaded case study is applied to a medical case, wherein the downloaded case is applied using deformable image registration to deform reference images of the downloaded case to medical images of the medical case. After application of the downloaded case study, the medical case is uploaded to the…
Particle beam gun control systems and methods
Granted: October 25, 2022
Patent Number:
11478664
Presented systems and methods facilitate efficient and effective monitoring of particle beams. In some embodiments, a radiation gun system comprises: a particle beam gun that generates a particle beam, and a gun control component that controls the gun particle beam generation characteristics, including particle beam fidelity characteristics. The particle beam characteristics can be compatible with FLASH radiation therapy. Resolution control of the particle beam generation can enable dose…
Imagers in radiation therapy environment
Granted: October 25, 2022
Patent Number:
11478663
An imager includes: an array of imager elements configured to generate image signals based on radiation received by the imager; and circuit configured to perform readout of image signals, wherein the circuit is configured to be radiation hard. An imager includes: an array of imager elements configured to generate image signals based on the radiation received by the imager; and readout and control circuit coupled to the array of imager elements, wherein the readout and control circuit is…
Trajectory optimization using dose estimation and conflict detection
Granted: October 25, 2022
Patent Number:
11478661
Systems and methods for radiation treatment planning can include a computing system determining an estimate of a radiation dose distribution within an anatomical region of a patient, and determining a cost matrix representing an objective function, using the estimate of the radiation dose distribution. The computing system can project the cost matrix on each of a plurality of fluence planes. Each of the plurality of fluence planes can be associated with a corresponding gantry-couch…
Automatically-planned radiation-based treatment
Granted: October 25, 2022
Patent Number:
11478660
Deep learning approaches automatically segment at least some breast tissue images while non-deep learning approaches automatically segment organs-at-risk. Both three-dimensional CT imaging information and two-dimensional orthogonal topogram imaging information can be used to determine virtual-skin volume. The foregoing imaging information can also serve to automatically determine a body outline for at least a portion of the patient. That body outline, along with the virtual-skin volume…
Automatically-registered patient fixation device images
Granted: October 25, 2022
Patent Number:
11478210
A three-dimensional model for a patient fixation device that serves to immobilize at least a portion of a particular patient when capturing CT image information of that patient is accessed and then registered with the pixels that correspond to the patient fixation device in the CT image. The model can specify rules of movement for each of a plurality of structural elements that comprise the patient fixation device and that are capable of movement relative to one another. By one approach…
Knowledge-based automatic image segmentation
Granted: September 27, 2022
Patent Number:
11455732
A method for medical image segmentation. The method includes accessing and updating a knowledge-base in accordance with embodiments of the present invention. The techniques include: receiving a medical image and computing a sparse landmark signature based on the medical image content. Next, a knowledge-base is searched for representative matches to form a base set, wherein the base set comprises a plurality of reference image sets. A portion of the plurality of reference image sets of…
Interactive and intuitive method to shape 3D dose distribution during optimization of IMRT plans
Granted: September 20, 2022
Patent Number:
11449208
New techniques are described herein for providing a user-friendly interface for adjusting dose distribution values during optimization of a radiation application plan. In an embodiment, a graphical user interface is provided that provides an image of a target area for a radiation application, and a graphical overlay of a dose distribution disposed over the target area that visually represents the optimized dose distribution according to the input dose parameters. In one or more…
Hybrid trajectory and beam angle optimization for external beam radiation therapy
Granted: September 13, 2022
Patent Number:
11439842
A method of determining treatment geometries for a radiotherapy treatment includes providing a patient model having one or more regions of interest (ROIs); defining a delivery coordinate space (DCS); for each beam's eye view (BEV) plane of each vertex in the DCS, and for each ROI, evaluating a dose of the ROI using transport solutions; evaluating a BEV scores of each pixel of the BEV plane using the doses of the one or more ROIs; determining one or more BEV regions in the BEV plane based…
Systems and methods for treating a lung of a patient using guided radiation therapy or surgery
Granted: September 13, 2022
Patent Number:
11439847
Systems and methods for treating a lung of a patient. One embodiment of a method comprises positioning a leadless marker in the lung of the patient relative to the target, and collecting position data of the marker. This method further comprises determining the location of the marker in an external reference frame outside of the patient based on the collected position data, and providing an objective output in the external reference frame that is responsive to movement of the marker. The…
Knowledge based treatment planning corrected for biological effects
Granted: September 13, 2022
Patent Number:
11439843
Solutions are provided herein that specifically accounts for biological effects of tissue during radiation planning (such as treatment planning). In one or more embodiments, the biological effects may be calculated by accessing a knowledge base to determine reference data comprising at least one biological characteristic corresponding to the at least one organ, predicting a biological effect for the plurality of identified structures based on the biological characteristic corresponding…
