METHOD FOR PREDISTORTING SIGNALS FOR NON-LINEAR COMPONENTS IN THE PRESENCE OF LONG TERM MEMORY EFFECTS
Granted: May 30, 2013
Application Number:
20130138416
A method and system for predistorting signals provides a test signal to model a non-linear component. Model kernels representative of static and dynamic parts of the model are extracted from an output of the non-linear component responsive to the test signal. The dynamic part represents memory effects of the non-linear component. The model kernels are then used to calculate an inverse memory model component model. An input signal is predistorted using the inverse memory model.
PLASMA TORCH WITH MULTIPLE INLETS FOR GUIDING COOLING GAS
Granted: May 23, 2013
Application Number:
20130127324
A plasma torch comprises: a glass inner tube comprising an outlet where a plasma is formed; a glass outer tube comprising at least three inlets for receiving a cooling gas and distributing the cooling gas between the glass outer tube and the glass inner tube; and a cartridge housing comprising a gas receiving inlet, the glass outer tube being in fluid communication with the gas receiving inlet. Any two of the at least three inlets are radially offset by fewer than 180°.
USE OF DNAZYMES FOR ANALYSIS OF AN RNA SAMPLE
Granted: May 16, 2013
Application Number:
20130123129
Provided herein is method comprising: contacting an initial RNA sample containing a population of different RNA molecules with a divalent cation and a set of DNAzymes that are designed to cleave multiple target RNAs in the initial sample, thereby producing a product RNA sample that comprises: a) uncleaved RNA molecules and b) cleaved RNA fragments that contain a 2?,3?-cyclic-phosphate and a 5? hydroxyl as the result of DNAzyme cleavage.
MULTI-SITE MUTAGENESIS
Granted: May 16, 2013
Application Number:
20130122550
The present invention provides compositions and improved methods for multi-site directed mutagenesis and DNA shuffling. The present compositions and methods provide increased mutation frequency and increased number of transformants which allow one to sequence only a few clones in order to identify the correct mutants and to obtain the desired mutant by screening large number of transformants in a short time. Moreover, the inclusion of FEN-1, PEF and optimized buffer and cycling…
WESTERN BLOT ANALYTICAL TECHNIQUE
Granted: May 9, 2013
Application Number:
20130115714
In accordance with an embodiment of the present invention, there is provided a method of performing the western blot analytical technique, wherein the method comprises carrying out the following steps in the following order: a), pre-staining the proteins within a sample; b). separating the proteins using gel electrophoresis; c). analysing the separated proteins to determine the total protein load and/or at least one housekeeping protein load; d). transferring the proteins onto at least…
CALIBRATING RECONSTRUCTED SIGNAL USING MULTI-TONE CALIBRATION SIGNAL
Granted: May 2, 2013
Application Number:
20130110442
A method of calibrating a reconstructed signal from a plurality of sub-signals is provided. The method includes injecting a calibration signal having multiple tones into a received input signal; dividing the input signal into a first and second sub-signal, including an overlapping frequency band; performing a first frequency translation by converting frequency components of the second sub-signal; digitizing the first sub-signal and the frequency converted second sub-signal; performing a…
AUTOMATIC TUNING OF ATOMIC FORCE MICROSCOPE
Granted: May 2, 2013
Application Number:
20130110262
An atomic force microscope (AFM) comprises a physical system and a controller comprising a plurality of digital filters and configured to control the physical system. The AFM is tuned by performing automatic loop shaping on a loop response defined by a frequency response of the physical system and a frequency response of the controller, and adjusting a gain of the controller according to a peak in a magnitude of the loop response.
OSCILLOSCOPE PROBE COMPRISING STATUS INDICATOR
Granted: May 2, 2013
Application Number:
20130106401
A system comprises an oscilloscope and an oscilloscope probe having a status indicator. The status indicator is located on a probe head of the oscilloscope probe and is configured to convey information to a user to indicate at least one characteristic of the signal. In certain embodiments, the status indicator comprises a light or a screen to convey signal related information to the user.
IN-SITU CONDITIONING IN MASS SPECTROMETER SYSTEMS
Granted: April 25, 2013
Application Number:
20130099113
In a mass spectrometer or gas chromatograph/mass spectrometer system, a conditioning gas such as, for example, hydrogen is added to condition or clean one or more components or regions of the mass spectrometer such as the ion source. The conditioning gas may be added upstream of the mass spectrometer such as, for example, into a sample inlet or a chromatographic column, or may be added directly into the mass spectrometer. The conditioning gas may be added off-line, when the mass…
Inorganic/Organic Hybrid Totally Porous Metal Oxide Particles, Methods For Making Them And Separation Devices Using Them
Granted: April 25, 2013
Application Number:
20130102459
The present invention is a process for making an inorganic/organic hybrid totally porous spherical silica particles by self assembly of surfactants that serve as organic templates via pseudomorphic transformation.
REDUCING METASTABILITY IN ANALOG TO DIGITAL CONVERSION
Granted: April 4, 2013
Application Number:
20130082854
A system for performing analog-to-digital conversion comprises a sampling unit that generates multiple digital samples from an analog input signal at each recurrence of a periodic interval, and a processing unit that combines the digital samples to produce a digital output signal. In certain embodiments, the sampling unit comprises multiple analog-to-digital converters arranged in parallel, and the processing unit comprises a digital signal processor that detects outliers in the digital…
PARALLEL MAGNETIC RESONANCE IMAGING USING GLOBAL VOLUME ARRAY COIL
Granted: April 4, 2013
Application Number:
20130082709
A magnetic resonance imaging (MRI) apparatus comprises a plurality of cylindrical electromagnetic coils arranged in a coaxial configuration around a sample region. The coils are used to capture resonance signals from a sample at different times according to a geometric echo effect. The measurements can then be combined to produce an MRI signal.
CLOSED CORE CURRENT PROBE
Granted: April 4, 2013
Application Number:
20130082695
A current probe enabling measurement of current of a signal in a circuit includes a ferrite core defining a gap, a wire wrapped around the ferrite core and a magnetic field sensor. The wire is configured to receive the signal from the circuit, where the current of the signal flowing in the wire generates a magnetic field in the ferrite core. The magnetic field sensor is positioned in the gap of the ferrite core, the magnetic field generated in the ferrite core flowing through the…
CHARACTERIZATION AND CORRECTION OF VOLTAGE PROBE, CURRENT PROBE AND CABLE
Granted: March 28, 2013
Application Number:
20130076372
Responses of voltage and current probes are characterized or corrected. A voltage probe method includes measuring output of the voltage probe and a first output of a through, in response to an input signal applied to the through, with the voltage probe connected, measuring a second output of the through with the voltage probe disconnected, and characterizing the response of the voltage probe using the output of the voltage probe and the first and/or second outputs. A current probe method…
SINGLE INJECTION VALVE FOR HPLC COMBINING SAMPLE INTRODUCTION, WASH CYCLES AND DIAGNOSIS
Granted: March 21, 2013
Application Number:
20130067997
A switchable valve for a sample injector includes a first valve member and a second valve member that can moved with respect to the other. The first valve member includes a plurality of ports, the second valve member includes a plurality of fluid paths. The plurality of ports include eight circumferential ports distributed along a circumference and one central port arranged at a central position of the first valve member. The plurality of fluid paths include three arcuate fluid paths so…
IN-SITU CONDITIONING IN MASS SPECTROMETER SYSTEMS
Granted: March 14, 2013
Application Number:
20130062515
In a mass spectrometer or gas chromatograph/mass spectrometer system, a conditioning gas such as, for example, hydrogen is added to condition or clean one or more components or regions of the mass spectrometer such as the ion source. The conditioning gas may be added upstream of the mass spectrometer such as, for example, into a sample inlet or a chromatographic column, or may be added directly into the mass spectrometer. The conditioning gas may be added off-line, when the mass…
HIGH-VACUUM PUMP
Granted: February 21, 2013
Application Number:
20130045094
A high-vacuum pump comprises a plurality of pumping stages, each comprising a plurality of mutually cooperating elements, including at least one rotating rotor element and one stationary stator element. At least one of the elements of at least one of the pumping stages is made of a plastic material reinforced with short fibres, dispersed in chaotic and substantially random manner inside the matrix of plastic material. Use of a plastic material reinforced with short fibres allows making…
CALIBRATION OF MASS SPECTROMETRY SYSTEMS
Granted: February 21, 2013
Application Number:
20130043380
A method for operating a mass spectrometer (MS) includes establishing a pressure differential across a membrane wherein an upstream pressure in a calibrant gas inlet line on an upstream side of the membrane is greater than a downstream pressure in an ion source on a downstream side of the membrane; flowing a calibrant gas from the calibrant gas inlet line, through a nano-scale orifice of the membrane, and into the ion source; and maintaining the upstream pressure at a constant value. The…
USE OF N-ALKYL IMIDAZOLE FOR SULFURIZATION OF OLIGONUCLEOTIDES WITH AN ACETYL DISULFIDE
Granted: February 7, 2013
Application Number:
20130035261
A method and compositions for sulfurizing at least one phosphite or thiophosphite linkage in an oligonucleotide. The addition of N-alkyl imidazole to the acetyldisulfide sulfurization solution enables the use of industrially preferred solvents or solvents that are derived from renewable resources.
DRIFT STABILIZATION OF MAGNETICALLY TUNABLE FILTER BY TEMPERATURE REGULATION AND MECHANICAL ISOLATION OF ELCTROMAGNET COIL
Granted: January 31, 2013
Application Number:
20130027152
An electromagnet structure comprises a magnetic shell having a cavity, a magnetic pole located within the cavity and having a magnetic gap for focusing a magnetic field on a magnetically tunable filter, a conductive coil located within the cavity of the magnetic shell and forming multiple turns around the magnetic pole, and a heater located within the cavity of the magnetic shell and configured to maintain the conductive coil at a substantially constant temperature when the magnetically…