METHOD OF GENERATING INTERFERENCE SIGNALS AND DEVICE TO CARRY OUT SUCH A METHOD
Granted: August 8, 2013
Application Number:
20130202020
A method for generating interference signals and a device to carry out said method, in which an interference signal (1) is added in a signal combination and separation network (3) with a desired signal (4) that carries a test message, the sum signal being sent to a device being tested (5). The interference signal (1) is generated with a single source connected to a signal divider and conditioner block (7) that attenuates additional interference produced by the source of generation of…
CHARGE CORRECTION FOR PIEZOELECTRIC ACTUATOR
Granted: August 8, 2013
Application Number:
20130200751
A system comprises a voltage source, a piezoelectric material arranged in a first current path between the voltage source and a first reference voltage, a capacitor arranged in a second current path between the voltage source and a second reference voltage, and a correction circuit configured to adjust the first reference voltage to increase or decrease the current in the first current path according to the current in the second current path.
FERRULE CHUCK WITH SURFACE MICRO-GRIP
Granted: August 8, 2013
Application Number:
20130199981
A fitting for coupling a capillary to another component of a fluidic device is disclosed. The fitting includes a ferrule configured for enclosing a front part of the capillary and for contributing to a fluidic sealing between the fitting and the other component; a ferrule chuck configured for enclosing a back part of the capillary; and a housing configured for accommodating at least a part of the ferrule chuck and for pushing the ferrule chuck against the ferrule.
SYSTEM FOR MEASURING RESIDUAL PHASE NOISE
Granted: August 1, 2013
Application Number:
20130197848
A system for measuring residual phase noise of a device under test (DUT) includes first and second signal sources, first and second receivers, and a processor. The first signal source generates a first signal to be input to the DUT as a stimulus signal and provides a second signal that is phase coherent with the first signal. The second signal source receives the second signal and generates a reference signal based on the second signal, which is phase coherent with the stimulus signal.…
PHASE-CONTINUOUS TUNABLE LASER
Granted: August 1, 2013
Application Number:
20130195129
A tunable laser comprises a first tuner configured to select an emission wavelength of the laser a second tuner configured to adjust a cavity mode of the laser by modifying the cavity optical path length. The second tuner is constrained by a finite tuning range. The tunable laser also comprises a controller configured to control the first and second tuners to select the emission wavelength and adjust the cavity mode in synchronization to perform phase-continuous tuning across a range…
COMPACT, ULTRA-BROADBAND ANTENNA WITH DOUGHNUT-LIKE RADIATION PATTERN
Granted: August 1, 2013
Application Number:
20130194160
A compact, ultra-broadband antenna with doughnut-like radiation pattern is provided as including a first assembly having first and second ends; a second assembly having first and second ends, the first and second ends each configured to have a substantially hemispherical shape; and a cable configured to extend through the first and second assemblies and out each of the first and second ends.
ION SOURCE FOR MASS SPECTROMETERS
Granted: August 1, 2013
Application Number:
20130193318
Ion sources for use in mass spectrometry (MS) systems are described. The ion sources each comprise an ion funnel and an ionization source configured to ionize neutral analyte molecules.
LOW NOISE BACK PRESSURE REGULATOR FOR SUPERCRITICAL FLUID CHROMATOGRAPHY
Granted: August 1, 2013
Application Number:
20130192698
A drive mechanism for back pressure regulator used in liquid chromatography, supercritical fluid chromatography, or supercritical fluid extraction allows very fine automated control over a very wide range of pressures by combining a linear actuator compressing a spring, pushing a pin. The nozzle assembly of the regulator comprises a flow through chamber containing a diaphragm and a seat, in which the pin pushes the diaphragm against the seat, together with an upstream pressure sensor and…
SYSTEM AND PROCESS FOR AN ACTIVE DRAIN FOR GAS-LIQUID SEPARATORS
Granted: July 18, 2013
Application Number:
20130180404
An apparatus and process to effectively create an active drain for high and low pressure gas-liquid separator. The invention accomplishes a deterministic drainage rate of variable volume and viscosity liquid fractions from the separator. The mechanisms and methods thereof create a flow path from the separator that dramatically favors controlled liquid flow over a wide range of flow rates and viscosities while restricting gas flow. The invention is a superior method of drainage over…
NUCLEAR MAGNETIC RESONANCE PROBE COMPRISING INFRARED REFLECTION PATCHES
Granted: July 11, 2013
Application Number:
20130178366
A nuclear magnetic resonance (NMR) probe comprises a substrate, a probe coil formed on the substrate and comprising a superconducting material, and a plurality of infrared (IR) reflection patches formed on the substrate around the probe coil.
INDUCTIVELY COUPLED PLASMA MS/MS MASS ANALYZER
Granted: July 11, 2013
Application Number:
20130175442
An inductively coupled plasma MS/MS mass analyzer (ICP-MS/MS) may include a first vacuum chamber which draws plasma containing an ionized sample into vacuum, a second vacuum chamber which includes a device or means which extracts and guides ions as an ion beam from the ions output from the first vacuum chamber, a third vacuum chamber which has a first ion optical separation device or means, a fourth vacuum chamber which has a cell into which reaction gas is introduced, and a fifth vacuum…
RADIO FREQUENCY (RF) ION GUIDE FOR IMPROVED PERFORMANCE IN MASS SPECTROMETERS
Granted: July 11, 2013
Application Number:
20130175440
Ion guides for use in mass spectrometry (MS) systems are described. The ion guides are configured to provide a reflective electrodynamic field and a direct current (DC or static) electric field to provide ion beams that are more spatially confined with a comparatively large mass range.
OPTICAL COHERENT RECEIVER WITH LOCAL OSCILLATOR LASER HAVING HYBRID CAVITY
Granted: July 4, 2013
Application Number:
20130170843
A coherent optical receiver includes a local oscillator (LO) laser configured to provide an LO signal. The LO laser includes a hybrid external cavity and an active gain medium within the hybrid external cavity, where the LO laser is defined between a first optical reflector on a chip including the active gain medium and a second optical reflector not on the chip.
DETECTING RESPONSES OF MICRO-ELECTROMECHANICAL SYSTEM (MEMS) RESONATOR DEVICE
Granted: July 4, 2013
Application Number:
20130169341
A system for detecting responses of a MEMS resonator device includes first and second signal sources, a signal divider and a frequency mixer. The first signal source provides a first signal and the second signal source provides a second signal that electrostatically drives the MEMS resonator device, causing mechanical vibration. The signal divider divides the first signal into a probe signal and a local oscillator (LO) signal, the probe signal being applied to the MEMS resonator device…
ADJUSTABLE APERTURE DEVICE WITH INTEGRAL APERTURE HOLES
Granted: June 27, 2013
Application Number:
20130161517
An adjustable aperture device for an electromagnetic radiation detecting apparatus includes a position adjustment body configured for adjusting a position of a selected aperture hole of multiple selectable aperture holes, where electromagnetic radiation propagates through the selected aperture hole. The adjustable aperture device further includes a guide unit configured for guiding the position adjustment body along a predefined guide direction, and an aperture body defining the aperture…
DATA ACQUISITION MODES FOR ION MOBILITY TIME-OF-FLIGHT MASS SPECTROMETRY
Granted: June 27, 2013
Application Number:
20130161506
Methods, apparatus and systems for acquiring spectrometric data from analyte ions implement a combination of drift-type ion mobility (IM) separation and time-of-flight mass spectrometry (TOF MS). Both separation techniques are carried out in tandem while applying mass filtering with a wide window of ion isolation. One mode of operation entails utilizing a mass filter to limit ion packets to ions in a selected m/z range that remains constant over the entire course of data acquisition.…
FITTING ELEMENT WITH HYDRAULIC GRIP FORCE ELEMENT
Granted: May 30, 2013
Application Number:
20130134082
A fitting element (100), in particular for an HPLC application (10), is configured for providing a fluidic coupling of a tubing (102) to a fluidic device (103). The fitting element (100) comprises a gripping piece (108) to exert—upon coupling of the tubing (102) to the fluidic device (103)—a grip force (G) between the fitting element (100) and the tubing (102). The gripping piece (108) comprises a hydraulic element (170) configured to transform an axial force (S) into a hydraulic…
NOVEL METHODS FOR THE SYNTHESIS AND PURIFICATION OF OLIGOMERS
Granted: May 30, 2013
Application Number:
20130137861
A reagent for oligonucleotide synthesis or purification, wherein the reagent has a structure of: X—C-L-H??(Formula A) wherein X is a phosphoramidite group, an H-phosphonate group, an acetal group, or an isocyanate; C is a direct bond or a cleavable adaptor represented by —Ca-Cb—; L is a hydrocarbyl chain; and H is a terminal alkyne or an activated cyclooctyne. The reagent of Formula (A) can be used in the synthesis and purification of oligonucleotides.
QUANTITATIVE PCR-BASED METHOD TO PREDICT THE EFFICIENCY OF TARGET ENRICHMENT FOR NEXT-GENERATION SEQUENCING USING REPETITIVE DNA ELEMENTS (LINES/SINES) AS NEGATIVE CONTROLS
Granted: May 30, 2013
Application Number:
20130137582
A method for determining an efficiency of target enrichment from a DNA library, includes: adding a negative control sequence and a positive control sequence to the DNA library, or picking a negative control sequence and/or a positive control sequence from the library; determining a pre-capture amount of the negative control sequence and a pre-capture amount of the positive control sequence; performing enrichment of a target sequence from the DNA library using a bait sequence to produce a…
TWO-DIMENSIONAL LIQUID CHROMATOGRAPHY WITH CONTROL OF INJECTION IN RELATION TO A STATE OF THE SECOND DIMENSION CHROMATOGRAPH
Granted: May 30, 2013
Application Number:
20130134095
A two-dimensional liquid chromatography in a system (200) comprises a first liquid chromatograph (210) coupled with a second liquid chromatograph (220). An injection event of injecting an output of the first liquid chromatograph (210) into the second liquid chromatograph (220) is controlled (290) in relation to a state (600, 610; 620, 630) of the second liquid chromatograph (220). FIG. 6A for publication
