Waste water purification
Granted: May 24, 1983
Patent Number:
4384956
A novel process for the purification of waste water and/or waste water sludge comprising subjecting the waste water and/or waste water sludge to first a methane fermentation step, then a denitrification step and finally an oxidation step by aeration, the electron donor in the denitrification step being mainly the sulfide from the methane fermentation step and the remaining reduced compounds in the liquid effluent from the methane fermentation step being oxidized in the aeration step.
Preparation of 7-acylamino-3-(thio-substituted)-methyl 3-cephem-4-carboxylic acid-1-oxide derivatives
Granted: April 12, 1983
Patent Number:
4379923
A novel process for the preparation of 7-acylamino-3-(thio-substituted)-methyl-3-cephem-4-carboxylic acid 1-oxide derivatives comprising reacting a 7-acylamino-3-bromomethyl-3-cephem-4-carboxylic acid-1-oxide derivative with a silylated thiol of the formulaR--S--Si(CH.sub.3).sub.3 Iwherein R is an organic group, preferably a 5- or 6-membered heterocyclic group, which reaction is preferably carried out in the presence of an inert organic solvent at a temperature between -20.degree. and…
Process for preparing 3'bromo-desacetoxycephalosporanic acid sulfoxide compounds
Granted: December 28, 1982
Patent Number:
4366315
An improved process for the preparation of 3'-bromo-desacetoxycephalosphoranic acid sulfoxide compounds comprising protecting the 4-carboxy group of a 3'-unsubstituted cephalosporanic acid sulfoxide by silylating in an inert anhydrous organic solvent and brominating the silylated compound in situ which 3'-bromo compounds are valuable intermediates for the preparation of therapeutically useful cephalosporanic acid compounds.
Novel polyvalent virus vaccine against rabies and canine distemper
Granted: November 9, 1982
Patent Number:
4358438
A polyvalent virus vaccine for immunization of warm-blooded animals comprising a mixture of a rabies virus, preferably rabies strain No. 675 deposited in the Czechoslovak National Collection of Type Cultures of the Institute of Hygiene and Epidemiology in Prague under No. CNCTC No. A 04/77, and a canine distemper virus, said mixture being substantially free of material emanating from more than one type of tissue cell used to propagate the viruses and a process for its preparation by…
Process for preparing cephalosporanic acid compounds
Granted: November 9, 1982
Patent Number:
4358588
A process for the preparation of [D-.alpha.-amino-p-hydroxyphenylacetamido]-penicillanic acid or cephalosporanic acid compounds comprising reacting a compound having a formula selected from the group consisting of ##STR1## wherein X is selected from the group consisting of hydrogen, acetoxy and five-membered heterocyclic group containing at least one hetero atom of the group consisting of oxygen, sulfur and nitrogen and optionally substituted with e.g. lower alkyl, this residue being…
Infectious bronchitis vaccine for poultry
Granted: November 2, 1982
Patent Number:
4357320
Infectious bronchitis (IB) vaccines for poultry derived from at least one novel virus strain of novel infectious bronchitis serotypes, selected from the group consisting of culture Nos. CNCTC A 07/80, CNCTC A 08/80, CNCTC A 09/80, CNCTC A 010/80, CNCTC A 011/80, CNCTC A 013/80, CNCTC A 014/80, CNCTC A 015/80 and CNCTC A 016/80 deposited at the Czechoslovak National Collection of Type Cultures of the Institute of Hygiene and Epidemiology in Prague, Czechoslovakia and the novel viruses per…
Novel polyvalent virus vaccine
Granted: September 28, 1982
Patent Number:
4351827
A polyvalent virus vaccine for immunization of warm-blooded animals comprising a mixture of a rabies virus, preferably rabies strain No. 675 deposited in the Czechoslovak National Collection of Type Cultures of the Institute of Hygiene and Epidemiology in Prague under No. CNCTC No. A 04/77, and a canine distemper virus, said mixture being substantially free of material emanating from more than one type of tissue cell used to propagate the viruses and a process for its preparation by…
Potato snack and preparation thereof
Granted: September 7, 1982
Patent Number:
4348417
A process for the preparation of a novel potato snack product comprising mixing together a starch containing component, an active yeast, preferably baker's yeast, water and a sugar fermentable by the said yeast to form a dough mass, optionally dividing the dough into pieces, fermenting the dough mass or pieces for a period of time and temperature sufficient to form a light structure and frying in hot edible oil or fat or baking at ordinary oven temperatures the fermented dough or pieces…
Cephalosporin intermediates
Granted: August 31, 1982
Patent Number:
4347358
Novel bromo-substituted deacetoxycephalosporins of the formula ##STR1## wherein R.sub.1 is selected from the group consisting of benzamido, formamido, phenylacetamido and phenoxyacetamido, R.sub.2 is selected from the group consisting of hydrogen and bromine and R.sub.3 is a silyl group of the formula ##STR2## wherein R', R" and R'" are individually selected from the group consisting of alkyl of 1 to 6 carbon atoms, a halogen-substituted alkyl of 1 to 6 carbon atoms and aryl, which are…
Active dried baker's yeast
Granted: July 27, 1982
Patent Number:
4341871
An active dried baker's yeast having a protein content of 47 to 60% and a high gas production is obtained from new yeast hybrids selected from the group consisting of Ng 2031 and Ng 2103. Drying is carried out by dividing fresh compressed yeast into particles and drying the particles to a dry matter content of at least 85% by contacting the yeast with a drying gas at a temperature of not more than 160.degree. C. in not more than 120 minutes so that the temperature of the yeast particles…
Sucrose ester treatment of bananas
Granted: July 6, 1982
Patent Number:
4338342
A process for the treatment of fruits and vegetables to improve their shelf life and/or to decrease their loss of moisture and the fruits and vegetables treated by such a process and to compositions to be used in the said process wherein fruits and vegetables which are not over-ripe, i.e., to unripe fruits, to fruits which are just ripe or to partially ripened fruits are treated with an aqueous solution or suspension of sucrose esters of fatty acids.
Rabies virus vaccine
Granted: March 16, 1982
Patent Number:
4320115
A novel rabies virus strain No. 675 deposited in the Czechoslovak National Collection of Type Cultures of the Institute of Hygiene and Epidemiology in Prague under number CNCTO AO 4/77, novel living or inactivated cell culture vaccines derived therefrom, a process for the isolation of the virus strain as well as a process for the preparation of the said vaccines and novel method of immunizing warm-blooded animals against rabies.
Process for the production of carrier particles from yeast cells and for producing diagnostic agents therefrom and test kits containing such agents
Granted: March 16, 1982
Patent Number:
4320194
Yeast cells are converted into carrier particles useful as carriers for proteins and other materials useful in agglutination tests by cross-linking the proteins of the cell cytoplasm followed by stabilization of the carbohydrates of the cell wall by reaction with an epoxide. The stabilized cells obtained may be dyed and may be esterified or etherified to block the hydroxyl groups in their surfaces. They may be coupled to the protein or other material by activation, e.g. with cyanuric…
Sodium amoxicillin solvate
Granted: March 9, 1982
Patent Number:
4318852
The solvate of sodium amoxicillin and N-methyl-2-pyrrolidone and its preparation which is a stable antibiotic from which injectable solutions may be prepared.
Closure treatment machine
Granted: October 27, 1981
Patent Number:
4296769
A closure treatment machine having one or more caskets (1) for holding the closures (9); said caskets comprise a number of parallel bars (2, 3, 4), which are connected at both ends to each other by coupling plates (5, 6), whereby the parallel bars are arranged in such a way that the closures are held between said bars but still do have such a tolerance, that the cleansing liquid sprayed from nozzles (23) towards the closures may reach any side of the closures. For filling and emptying…
Process for the preparation of azetidines
Granted: August 4, 1981
Patent Number:
4282145
New azetidine derivatives of the formula: ##STR1## wherein R.sub.1 represents a penicillin- or cephalosporin-amido group, R.sub.2 represents one of the groups of the following formulae: ##STR2## wherein R.sub.4, R.sub.5 and R.sub.6 are the same or different and each represents a hydrogen atom or a lower alkyl or alkenyl group, n represents 2 or 3 and--in case formula IIB represents a phenyl group--this group may carry one to four further substituents selected from the group consisting of…
Microbial rennin
Granted: July 7, 1981
Patent Number:
RE30669
The production of a rennin of high milk coagulating activity and low proteolytic activity from a selected strain of Mucor miehei which is useful in cheese making.
New process for the preparation 17.beta.-hydroxy-3-oxo-17.alpha.-pregnene and pregnadiene-21-carboxylic acid .gamma.-lactones
Granted: May 12, 1981
Patent Number:
4267106
A process is disclosed for the preparation of 17.beta.-hydroxy-3-oxo-l7.alpha.-pregn-4-ene-21-carboxylic acid .gamma.-lactone and 17.beta.-hydroxy-3-oxo-17.alpha.-pregna-4,6-diene-21-carboxylic acid .gamma.-lactone of the formula: ##STR1## wherein the dotted line between the 6-7 positions indicates an optional double bond, which is present in the latter compound, by reacting an androst-5-ene-17-one derivative with an organo-phosphorus compound. These lactones are valuable intermediates…
Alkaline protease produced by a bacillus
Granted: May 5, 1981
Patent Number:
RE30602
A novel enzyme having a high proteolytic activity in alkaline media and being suitable for inclusion in washing compositions and which is produced by a novel Bacillus strain designated "PB 92", or its proteolytic enzyme producing mutants or variants. A culture of the Bacillus is deposited with the Laboratory for Microbiology of the Technical University of Delft, The Netherlands, where it has been given number OR-60.
Piperazine derivatives
Granted: May 5, 1981
Patent Number:
4265894
Piperazine derivatives of the general formula ##STR1## wherein R.sub.1 -R.sub.9 are the same or different and each represents a hydrogen or halogen atom or a lower alkyl or lower alkoxy group, n is 2 or 3 and X represents a group (CH.sub.2).sub.m (in which m is 1, 2, 3 or 4) or a group --CH.sub.2 --CH.dbd.CH--, having methylene linked to the piperazine group, and acid addition and quaternary ammonium salts thereof, are described.The compounds exhibit a strong specific dopaminergic…
