MOTION ARTIFACT REDUCTION IN COMPUTED TOMOGRAPHY
Granted: October 6, 2022
Application Number:
20220313181
A method of imaging a region of patient anatomy having a target volume includes performing an autosegmentation of a high-contrast portion of a first reconstructed volume of the region to generate a three-dimensional (3D) representation of the high-contrast portion disposed within the region and generating a set of two-dimensional (2D) mask projections of the region by performing a forward projection process on the 3D representation, wherein each 2D mask projection in the set of 2D mask…
MAGNETORESISTIVE ROTATIONAL POSITION DETECTION IN A RADIATION THERAPY SYSTEM
Granted: April 21, 2022
Application Number:
20220120588
A method of measuring a rotational position of an assembly with circumferential ferromagnetic teeth includes applying an excitation signal for a cycle to an actuator, the cycle causing a first rotational displacement of a first ferromagnetic tooth from a first rotational position to a second rotational position and a second rotational displacement of a second ferromagnetic tooth from the second rotational position to a third rotational position. The method further includes measuring a…
MAGNETORESISTIVE LINEAR POSITION DETECTION IN A RADIATION THERAPY SYSTEM
Granted: April 21, 2022
Application Number:
20220118286
A multileaf collimator includes a plurality of movable leaves for shaping a radiotherapy beam, wherein each leaf is independently movable in a same linear travel direction. Each leaf includes a linear array of magnets disposed on a measurement surface of the leaf and an array of magnetoresistive sensors that is disposed proximate the measurement surfaces of the leaves.
RADIATION TREATMENT PLANNING AND DELIVERY FOR MOVING TARGETS IN THE HEART
Granted: April 21, 2022
Application Number:
20220118285
Methods and systems are disclosed for radiating a moving object. The method may comprise acquiring a plurality of indicators of the phase of a physiological cycle of a patient and a plurality of images of the patient that include a target. Each image may be taken at a different phase of the physiological cycle and may be registered to the phase at which the image was taken. The method may also include identifying the target in each of the plurality of images, calculating a dose of…
METHODS AND SYSTEMS FOR RADIOTHERAPY TREATMENT PLANNING BASED ON DEEP TRANSFER LEARNING
Granted: February 17, 2022
Application Number:
20220051781
Example methods and systems for deep transfer learning for radiotherapy treatment planning are provided. One example method may comprise: obtaining (310) a base deep learning engine that is pre-trained to perform a base radiotherapy treatment planning task; and based on the base deep learning engine, generating a target deep learning engine to perform a target radiotherapy treatment planning task. The target deep learning engine may be generated by configuring (330) a variable base layer…
METHODS OF USE OF ULTRA-HIGH DOSE RATE RADIATION AND THERAPEUTIC AGENT
Granted: January 13, 2022
Application Number:
20220008750
Methods for treating tumors by administering FLASH radiation and a therapeutic agent to a patient with cancer are disclosed. The methods provide the dual benefits of anti-tumor efficacy plus normal tissue protection when combining therapeutic agents with FLASH radiation to treat cancer patients. The methods described herein also allow for the classification of patients into groups for receiving optimized radiation treatment in combination with a therapeutic agent based on…
RADIATION THERAPY SYSTEM USING A DIGITAL TOMOSYNTHESIS PROCESS FOR NEAR REAL-TIME LOCALIZATION
Granted: December 23, 2021
Application Number:
20210393989
A method of radiation therapy comprises, while a gantry of a radiation therapy system rotates continuously in a first direction through a treatment arc from a first treatment delivery position to a second treatment delivery position, causing an imaging X-ray source mounted on the gantry to direct X-rays through a target volume and receiving a set of X-ray projection images from an X-ray imager mounted on the gantry; determining a current location of the target volume based on the set of…
USING REINFORCEMENT LEARNING IN RADIATION TREATMENT PLANNING OPTIMIZATION TO LOCATE DOSE-VOLUME OBJECTIVES
Granted: December 9, 2021
Application Number:
20210379404
A reinforcement learning agent facilitates optimization of a radiation-delivery treatment plan. The reinforcement learning agent is configured to generate a radiation-delivery treatment plan that can exceed the quality of a plan or plans employed to train the reinforcement learning agent. The reinforcement learning agent is trained to evaluate a radiation-delivery treatment plan that is output by an optimization software application, modify one or more dose-volume objective parameters of…
TIME-DOMAIN INTERLEAVING OF IMAGING AND TREATMENT X-RAYS IN A RADIATION THERAPY SYSTEM
Granted: November 18, 2021
Application Number:
20210353964
Time-domain interleaving of treatment X-rays and imaging X-rays during an image guided radiation therapy (IGRT) process in a radiation therapy system prevents scatter of the treatment X-rays from degrading the quality of X-ray images used to generate volumetric image data of a target volume. Imaging X-rays are delivered to the target volume during one or more imaging intervals, and one or more pulses of treatment X-rays are delivered to the target volume between the imaging intervals. In…
ELECTRONIC SHUTTER IN A RADIATION THERAPY SYSTEM
Granted: November 11, 2021
Application Number:
20210346723
In a radiation therapy system, treatment X-rays are delivered to a target volume at the same time that imaging X-rays are also delivered to the target volume for generating image data of the target volume. That is, during an imaging interval in which imaging X-rays are delivered to the target volume, one or more pulses of treatment X-rays are also delivered to the target volume. In each pixel of an X-ray imaging device of the radiation therapy system, image signal is accumulated during…
PATIENT SUPPORTS FOR MEDICAL TREATMENTS
Granted: October 7, 2021
Application Number:
20210308483
A patient supporting device includes: a base; a positioner; a platform having a first end and a second end; and a controller; wherein the positioner is operable by the controller to place the platform at one of a first plurality of possible positions or at one of a second plurality of possible positions, wherein in any of the first plurality of possible positions, the second end of the platform is closer to one of a left side and a right side of a treatment machine; wherein in any of the…
RADIOTHERAPY TREATMENT PLANNING BASED ON TREATMENT DELIVERY EFFICIENCY
Granted: September 30, 2021
Application Number:
20210299469
Example methods and systems for radiotherapy treatment planning based on treatment delivery efficiency are described. One example method may comprise a computer system configuring dosimetric planning objective(s) and non-dosimetric planning objective(s) associated with efficiency of treatment delivery. A set of multiple treatment plan variants may be generated based on the dosimetric planning objective(s) and non-dosimetric planning objective(s). A first treatment plan associated with a…
Color-Coded Polymeric Particles of Predetermined Size for Therapeutic and/or Diagnostic Applications and Related Methods
Granted: September 30, 2021
Application Number:
20210299056
Various embodiments are directed to color-coded and size-calibrated polymeric particles comprising an acrylate-based hydrogel core incorporating one or more chromophores of interest, and an outer shell comprising polyphosphazenes of formula I, useful for various therapeutic and/or diagnostic procedures. In various embodiments, the color-coded and size-calibrated polymeric particles can be employed in any particle-mediated procedure, including as embolic agents, dermal fillers, and…
CONE-BEAM COMPUTED TOMOGRAPHY IMAGING DEVICES, SYSTEMS, AND METHODS
Granted: September 9, 2021
Application Number:
20210275112
Cone-beam computer tomography systems, devices, and methods for image acquisition of large target volumes using partial scans.
SINGLE-PASS IMAGING AND RADIATION TREATMENT DELIVERY VIA AN EXTENDED ROTATION GANTRY
Granted: July 1, 2021
Application Number:
20210196985
An example method of radiation therapy in a radiation therapy system that includes a gantry with a treatment-delivering X-ray source and an imaging X-ray source mounted thereon is described. The method includes rotating the gantry in a first direction at a first rotational velocity about an open bore and concurrently rotating an annular support structure at a second rotational velocity about the open bore, wherein the second rotational velocity is less than the first rotational velocity.…
TOMOGRAPHIC IMAGE ANALYSIS USING ARTIFICIAL INTELLIGENCE (AI) ENGINES
Granted: June 24, 2021
Application Number:
20210192810
Example methods and systems for tomographic data analysis are provided. One example method may comprise: obtaining first three-dimensional (3D) feature volume data and processing the first 3D feature volume data using an AI engine that includes multiple first processing layers, an interposing forward-projection module and multiple second processing layers. Example processing using the AI engine may involve: generating second 3D feature volume data by processing the first 3D feature…
TOMOGRAPHIC IMAGE RECONSTRUCTION USING ARTIFICIAL INTELLIGENCE (AI) ENGINES
Granted: June 24, 2021
Application Number:
20210192809
Example methods and systems for tomographic image reconstruction are provided. One example method may comprise: obtaining two-dimensional (2D) projection data and processing the 2D projection data using the AI engine that includes multiple first processing layers, an interposing back-projection module and multiple second processing layers. Example processing using the AI engine may involve: generating 2D feature data by processing the 2D projection data using the multiple first…
TRAINING DEEP LEARNING ENGINES FOR RADIOTHERAPY TREATMENT PLANNING
Granted: June 24, 2021
Application Number:
20210192719
Example methods and systems for training deep learning engines for radiotherapy treatment planning are provided. One example method may comprise: obtaining a set of training data that includes unlabeled training data and labeled training data; and configuring a deep learning engine to include (a) a primary network and (b) a deep supervision network that branches off from the primary network. The method may further comprise: training the deep learning engine to perform the radiotherapy…
INCORPORATING MULTIPLE TARGETS IN TRAJECTORY OPTIMIZATION FOR RADIOTHERAPY TREATMENT PLANNING
Granted: June 17, 2021
Application Number:
20210178188
Methods of treatment trajectory optimization for radiotherapy treatment of multiple targets include determining beam's eye view (BEV) regions and a BEV region connectivity manifold for each target group of a plurality of target groups separately. The information contained in the BEV regions and the BEV region connectivity manifolds for all target groups is used to guide an optimizer to find optimal treatment trajectories. To improve the visibility of insufficiently exposed voxels of…
BEAM ANGLE OPTIMIZATION FOR EXTERNAL BEAM RADIATION THERAPY USING SECTIONING
Granted: June 17, 2021
Application Number:
20210178189
Methods of beam angle optimization for intensity modulated radiotherapy (IMRT) treatment include determining beam's eye view (BEV) regions and a BEV region connectivity manifold by evaluating dose response of each region of interest for each vertex in a delivery coordinate space (DCS). The information contained in the BEV regions and the BEV region connectivity manifold is used to guide an optimizer to find optimal field geometries in the IMRT treatment. To improve the visibility of…
