INCORPORATING MULTIPLE TARGETS IN TRAJECTORY OPTIMIZATION FOR RADIOTHERAPY TREATMENT PLANNING
Granted: June 17, 2021
Application Number:
20210178188
Methods of treatment trajectory optimization for radiotherapy treatment of multiple targets include determining beam's eye view (BEV) regions and a BEV region connectivity manifold for each target group of a plurality of target groups separately. The information contained in the BEV regions and the BEV region connectivity manifolds for all target groups is used to guide an optimizer to find optimal treatment trajectories. To improve the visibility of insufficiently exposed voxels of…
STATISTICAL METHOD FOR MATERIAL PROPERTY EXTRACTION FROM MULTI-ENERGY IMAGES
Granted: June 17, 2021
Application Number:
20210177366
An apparatus for determining material property, includes: an interface configured to obtain a first HU value associated with a first image of an object, and to obtain a second HU value associated with a second image of the object, wherein the first image is created using a first energy having a first energy level, and wherein the second image is created using a second energy having a second energy level that is different from the first energy level; and a processing unit configured to…
DEFORMABLE IMAGE REGISTRATION BASED ON AN IMAGE MASK
Granted: May 13, 2021
Application Number:
20210142494
In accordance with at least some embodiments of the present disclosure, a process to improve computed tomography (CT) to cone beam computed tomography (CBCT) registration is disclosed. The process may include receiving a CT image generated by CT-scanning of an object, and receiving a CBCT image generated by CBCT-scanning of the object. The process may include generating an image mask based on Digital Imaging and Communications in Medicine (DICOM) information extracted from the CBCT…
EXPANSION OF SEARCH SPACE FOR MULTICRITERIA OPTIMIZATION IN RADIATION TREATMENT PLANNING
Granted: May 13, 2021
Application Number:
20210138267
A search space used for multicriteria optimization in radiation treatment planning can be expanded using extrapolation. For instance, given an initial set of base plans, one or more virtual plans can be generated by assigning a weight to each base plan such that at least one of the weights is less than zero and/or such that the sum of the weights is not normalized to 1. The dose distribution for the virtual plan is computed as the weighted sum of the dose distributions of the base plans.…
BIOMARKERS FOR RADIATION TREATMENT
Granted: March 4, 2021
Application Number:
20210062277
The methods described herein allow for the classification of patients into groups for receiving optimized radiation treatment based on patient specific biomarker signature. The biomarker signature includes markers that have been shown to correlate with TGF-B expression and to be associated with tumor aggressiveness, radioresistance and poor prognosis. The markers play a key role in the epithelial-mesenchymal transition. The methods described herein provide the dual benefits of anti-tumor…
QUALITY ASSURANCE PROCESS FOR RADIATION THERAPY TREATMENT PLANNING
Granted: December 24, 2020
Application Number:
20200398083
A method enables testing and evaluation of an expert human reviewer or an artificial intelligence (AI) error detection engine associated with a radiotherapy treatment planning process. Intentional errors are introduced into the output of a software module or AI engine that performs a certain step in the radiotherapy treatment planning process. The efficacy of the human or AI reviewer in detecting errors can then be evaluated or tested by determining whether the human or AI reviewer has…
METHODS AND SYSTEMS FOR QUALITY-AWARE CONTINUOUS LEARNING FOR RADIOTHERAPY TREATMENT PLANNING
Granted: December 24, 2020
Application Number:
20200398079
Example methods and systems for quality-aware continuous learning for radiotherapy treatment planning are provided. One example method may comprise: obtaining an artificial intelligence (AI) engine that is trained to perform a radiotherapy treatment planning task. The method may also comprise: based on input data associated with a patient, performing the radiotherapy treatment planning task using the AI engine to generate output data associated with the patient; and obtaining modified…
METHODS AND SYSTEMS FOR RADIOTHERAPY TREATMENT PLANNING BASED ON CONTINUOUS DEEP LEARNING
Granted: December 10, 2020
Application Number:
20200388371
Example methods and systems for radiotherapy treatment planning based on continuous deep learning are provided. One example method may comprise: obtaining a deep learning engine that is trained to perform a radiotherapy treatment planning task based on first training data associated with a first planning rule. The method may also comprise: based on input data associated with a particular patient, performing the radiotherapy treatment planning task using the deep learning engine to…
RADIATION THERAPY SYSTEM WITH FOLLOW-THE-LIGHTS USER INTERFACE
Granted: October 29, 2020
Application Number:
20200338366
Example methods and apparatuses of controlling a user interface with a plurality of input mechanisms are disclosed. One example method includes causing a first set of input mechanisms in the plurality of input mechanisms to be visually emphasized via a first visual technique while a second set of input mechanisms in the plurality of input mechanisms is not visually emphasized via the first visual technique, receiving a user input via an input mechanism that is included in the first set,…
IMAGE FUSION IN MULTI-LAYER FLAT PANEL IMAGER
Granted: October 15, 2020
Application Number:
20200326435
An imaging apparatus includes: a first scintillator layer configured to provide first image signals with a first quantum efficiency and a first spatial resolution; a second scintillator layer configured to provide second image signals with a second quantum efficiency and a second spatial resolution, wherein the first quantum efficiency is lower than the second quantum efficiency, but the first spatial resolution is higher than the second spatial resolution; and an image combiner…
USING ISODOSE SURFACES FOR OPTIMIZING DOSE DISTRIBUTION IN RADIATION TREATMENT PLANNING
Granted: October 1, 2020
Application Number:
20200306559
Cost functions and cost function gradients for use in radiation treatment planning can be computed based on an approximation of an “isodose” surface. Where a clinical goal is expressed by reference to a threshold isodose surface, a corresponding cost function component can be defined directly by reference to that isodose surface, and a corresponding contribution to the cost function gradient can be approximated by identifying voxels that are intersected by the threshold isodose…
IMAGING SYSTEMS AND METHODS
Granted: October 1, 2020
Application Number:
20200305807
An image acquisition apparatus includes: a positioner controller communicatively coupled to a positioner, wherein the positioner controller is configured to generate a control signal to cause the positioner to rectilinearly translate a patient support relative to an imager, and/or to rectilinearly translate the imager relative to the patient support; an imaging controller configured to operate the imager to generate a first plurality of two-dimensional images for a patient while the…
TEMPLATE MATCHING METHOD FOR IMAGE-BASED DETECTION AND TRACKING OF IRREGULAR SHAPED TARGETS
Granted: September 10, 2020
Application Number:
20200285915
A method of generating a template image includes: receiving an input from a user representing identifications of an object in different respective slices of a volumetric image; using the input to determine a volume-of-interest (VOI) that includes voxels in a subset of the volumetric image; and determining the template image using at least some of the voxels in the VOI, wherein the act of determining the template image comprises performing a forward projection of the at least some of the…
SYSTEMS AND METHODS FOR ENERGY MODULATED RADIATION THERAPY
Granted: July 16, 2020
Application Number:
20200227184
A method performed by a medical device, includes: providing a permanent magnetic field by a permanent magnet; operating an electromagnet to provide a first electromagnetic field with a first electromagnetic field value; and operating the electromagnet to provide a second electromagnetic field with a second electromagnetic field value; wherein the first electromagnetic field and the permanent magnetic field forms a first total magnetic field with a first total magnetic field value, and…
CREATING TREATMENT FIELD USING INITIAL FIELD AND PATIENT SPECIFIC GEOMETRY AND ACHIEVABLE DOSE
Granted: July 16, 2020
Application Number:
20200222720
Methods and systems are provided for developing radiation therapy treatment plans. A treatment template with radiation fields can be chosen for a patient based on a tumor location. Static radiation field positions can be adjusted for the patient, while arc radiation fields may remain the same. Static radiation field positions can be adjusted using dose gradient, historical patient data, and other techniques.
INCORPORATING MULTIPLE TARGETS IN TRAJECTORY OPTIMIZATION FOR RADIOTHERAPY TREATMENT PLANNING
Granted: July 2, 2020
Application Number:
20200206531
Methods of treatment trajectory optimization for radiotherapy treatment of multiple targets include determining beam's eye view (BEV) regions and a BEV region connectivity manifold for each target group of a plurality of target groups separately. The information contained in the BEV regions and the BEV region connectivity manifolds for all target groups is used to guide an optimizer to find optimal treatment trajectories. To improve the visibility of insufficiently exposed voxels of…
METHODS AND SYSTEMS FOR GENERATING DOSE ESTIMATION MODELS FOR RADIOTHERAPY TREATMENT PLANNING
Granted: June 25, 2020
Application Number:
20200197726
Example methods and systems for generating dose estimation models for radiotherapy treatment planning are provided. One example method may comprise obtaining model configuration data that specifies multiple anatomical structures based on which dose estimation is performed by a dose estimation model. The method may also comprise obtaining training data that includes a first treatment plan associated with a first past patient and multiple second treatment plans associated with respective…
IMMUNE MODULATORS IN COMBINATION WITH RADIATION TREATMENT
Granted: May 21, 2020
Application Number:
20200155680
Methods for treating tumors by administering ionizing radiation and an immune modulator to a patient with cancer are disclosed. The methods provide the dual benefits of anti-tumor efficacy plus normal tissue protection when combining immune modulators with ionizing radiation to treat cancer patients. The methods described herein also allow for the classification of patients into groups for receiving optimized radiation treatment in combination with an immune modulator based on…
ELECTROMAGNETIC INTERFERENCE CONTAINMENT FOR ACCELERATOR SYSTEMS
Granted: April 30, 2020
Application Number:
20200135423
An apparatus for coupling to an input connection of an electron gun, the input connection having a heater terminal and a cathode terminal, includes: a connector having a first end and a second end; wherein the first end of the connector is configured to attach to a cable; wherein the second end of the connector is configured to connect to the input connection of the electron gun; and wherein the connector comprises an opening configured to receive the heater terminal of the input…
HYBRID TRAJECTORY AND BEAM ANGLE OPTIMIZATION FOR EXTERNAL BEAM RADIATION THERAPY
Granted: April 2, 2020
Application Number:
20200101323
A method of determining treatment geometries for a radiotherapy treatment includes providing a patient model having one or more regions of interest (ROIs); defining a delivery coordinate space (DCS); for each beam's eye view (BEV) plane of each vertex in the DCS, and for each ROI, evaluating a dose of the ROI using transport solutions; evaluating a BEV scores of each pixel of the BEV plane using the doses of the one or more ROIs; determining one or more BEV regions in the BEV plane based…
