USING ISODOSE SURFACES FOR OPTIMIZING DOSE DISTRIBUTION IN RADIATION TREATMENT PLANNING
Granted: October 1, 2020
Application Number:
20200306559
Cost functions and cost function gradients for use in radiation treatment planning can be computed based on an approximation of an “isodose” surface. Where a clinical goal is expressed by reference to a threshold isodose surface, a corresponding cost function component can be defined directly by reference to that isodose surface, and a corresponding contribution to the cost function gradient can be approximated by identifying voxels that are intersected by the threshold isodose…
IMAGING SYSTEMS AND METHODS
Granted: October 1, 2020
Application Number:
20200305807
An image acquisition apparatus includes: a positioner controller communicatively coupled to a positioner, wherein the positioner controller is configured to generate a control signal to cause the positioner to rectilinearly translate a patient support relative to an imager, and/or to rectilinearly translate the imager relative to the patient support; an imaging controller configured to operate the imager to generate a first plurality of two-dimensional images for a patient while the…
TEMPLATE MATCHING METHOD FOR IMAGE-BASED DETECTION AND TRACKING OF IRREGULAR SHAPED TARGETS
Granted: September 10, 2020
Application Number:
20200285915
A method of generating a template image includes: receiving an input from a user representing identifications of an object in different respective slices of a volumetric image; using the input to determine a volume-of-interest (VOI) that includes voxels in a subset of the volumetric image; and determining the template image using at least some of the voxels in the VOI, wherein the act of determining the template image comprises performing a forward projection of the at least some of the…
SYSTEMS AND METHODS FOR ENERGY MODULATED RADIATION THERAPY
Granted: July 16, 2020
Application Number:
20200227184
A method performed by a medical device, includes: providing a permanent magnetic field by a permanent magnet; operating an electromagnet to provide a first electromagnetic field with a first electromagnetic field value; and operating the electromagnet to provide a second electromagnetic field with a second electromagnetic field value; wherein the first electromagnetic field and the permanent magnetic field forms a first total magnetic field with a first total magnetic field value, and…
CREATING TREATMENT FIELD USING INITIAL FIELD AND PATIENT SPECIFIC GEOMETRY AND ACHIEVABLE DOSE
Granted: July 16, 2020
Application Number:
20200222720
Methods and systems are provided for developing radiation therapy treatment plans. A treatment template with radiation fields can be chosen for a patient based on a tumor location. Static radiation field positions can be adjusted for the patient, while arc radiation fields may remain the same. Static radiation field positions can be adjusted using dose gradient, historical patient data, and other techniques.
INCORPORATING MULTIPLE TARGETS IN TRAJECTORY OPTIMIZATION FOR RADIOTHERAPY TREATMENT PLANNING
Granted: July 2, 2020
Application Number:
20200206531
Methods of treatment trajectory optimization for radiotherapy treatment of multiple targets include determining beam's eye view (BEV) regions and a BEV region connectivity manifold for each target group of a plurality of target groups separately. The information contained in the BEV regions and the BEV region connectivity manifolds for all target groups is used to guide an optimizer to find optimal treatment trajectories. To improve the visibility of insufficiently exposed voxels of…
METHODS AND SYSTEMS FOR GENERATING DOSE ESTIMATION MODELS FOR RADIOTHERAPY TREATMENT PLANNING
Granted: June 25, 2020
Application Number:
20200197726
Example methods and systems for generating dose estimation models for radiotherapy treatment planning are provided. One example method may comprise obtaining model configuration data that specifies multiple anatomical structures based on which dose estimation is performed by a dose estimation model. The method may also comprise obtaining training data that includes a first treatment plan associated with a first past patient and multiple second treatment plans associated with respective…
IMMUNE MODULATORS IN COMBINATION WITH RADIATION TREATMENT
Granted: May 21, 2020
Application Number:
20200155680
Methods for treating tumors by administering ionizing radiation and an immune modulator to a patient with cancer are disclosed. The methods provide the dual benefits of anti-tumor efficacy plus normal tissue protection when combining immune modulators with ionizing radiation to treat cancer patients. The methods described herein also allow for the classification of patients into groups for receiving optimized radiation treatment in combination with an immune modulator based on…
ELECTROMAGNETIC INTERFERENCE CONTAINMENT FOR ACCELERATOR SYSTEMS
Granted: April 30, 2020
Application Number:
20200135423
An apparatus for coupling to an input connection of an electron gun, the input connection having a heater terminal and a cathode terminal, includes: a connector having a first end and a second end; wherein the first end of the connector is configured to attach to a cable; wherein the second end of the connector is configured to connect to the input connection of the electron gun; and wherein the connector comprises an opening configured to receive the heater terminal of the input…
METHODS AND SYSTEMS FOR ADAPTIVE RADIOTHERAPY TREATMENT PLANNING USING DEEP LEARNING ENGINES
Granted: April 2, 2020
Application Number:
20200105399
Example methods for adaptive radiotherapy treatment planning using deep learning engines are provided. One example method may comprise obtaining treatment image data associated with a first imaging modality and planning image data associated with a second imaging modality. The treatment image data may be acquired during a treatment phase of a patient. Also, planning image data associated with a second imaging modality may be acquired prior to the treatment phase to generate a treatment…
METHODS AND SYSTEMS FOR ADAPTIVE RADIOTHERAPY TREATMENT PLANNING USING DEEP LEARNING ENGINES
Granted: April 2, 2020
Application Number:
20200105394
Example methods for adaptive radiotherapy treatment planning using deep learning engines are provided. One example method may comprise obtaining treatment image data associated with a first imaging modality. The treatment image data may be acquired during a treatment phase of a patient. Also, planning image data associated with a second imaging modality may be acquired prior to the treatment phase to generate a treatment plan for the patient. The method may also comprise: in response to…
METHODS AND SYSTEMS FOR RADIOTHERAPY TREATMENT PLANNING USING DEEP LEARNING ENGINES
Granted: April 2, 2020
Application Number:
20200104695
Example methods for radiotherapy treatment planning using deep learning engines are provided. One example method may comprise obtaining first image data associated with a patient; generating first feature data by processing the first image data associated with a first resolution level using a first processing pathway; generating second feature data by processing second image data associated with a second resolution level using a second processing pathway; and generating third feature…
ADJOINT TRANSPORT FOR DOSE IN BEAM ANGLE OPTIMIZATION FOR EXTERNAL BEAM RADIATION THERAPY
Granted: April 2, 2020
Application Number:
20200101325
A method of beam angle optimization for an IMRT radiotherapy treatment includes providing a patient model having one or more regions of interest (ROIs), defining a delivery coordinate space (DCS), for each ROI, solving an adjoint transport to obtain an adjoint solution field from the ROI, for each vertex in the DCS, evaluating an adjoint photon fluence by performing ray tracing of the adjoint solution field, evaluating a dose of the ROI using the adjoint photon fluence, for each vertex…
HYBRID TRAJECTORY AND BEAM ANGLE OPTIMIZATION FOR EXTERNAL BEAM RADIATION THERAPY
Granted: April 2, 2020
Application Number:
20200101323
A method of determining treatment geometries for a radiotherapy treatment includes providing a patient model having one or more regions of interest (ROIs); defining a delivery coordinate space (DCS); for each beam's eye view (BEV) plane of each vertex in the DCS, and for each ROI, evaluating a dose of the ROI using transport solutions; evaluating a BEV scores of each pixel of the BEV plane using the doses of the one or more ROIs; determining one or more BEV regions in the BEV plane based…
ADJOINT TRANSPORT FOR DOSE IN TREATMENT TRAJECTORY OPTIMIZATION FOR EXTERNAL BEAM RADIATION THERAPY
Granted: April 2, 2020
Application Number:
20200101322
A method of trajectory optimization for radiotherapy treatment includes providing a patient model having one or more regions of interest (ROIs), defining a delivery coordinate space (DCS), for each ROI, solving an adjoint transport to obtain an adjoint solution field from the ROI, for each vertex in the DCS, evaluating an adjoint photon fluence by performing ray tracing of the adjoint solution field, evaluating a dose of the ROI using the adjoint photon fluence, for each vertex in the…
BEAM ANGLE OPTIMIZATION FOR EXTERNAL BEAM RADIATION THERAPY USING SECTIONING
Granted: April 2, 2020
Application Number:
20200101320
Methods of beam angle optimization for intensity modulated radiotherapy (IMRT) treatment include determining beam's eye view (BEV) regions and a BEV region connectivity manifold by evaluating dose response of each region of interest for each vertex in a delivery coordinate space (DCS). The information contained in the BEV regions and the BEV region connectivity manifold is used to guide an optimizer to find optimal field geometries in the IMRT treatment. To improve the visibility of…
METHODS TO OPTIMIZE COVERAGE FOR MULTIPLE TARGETS SIMULTANEOUSLY FOR RADIATION TREATMENTS
Granted: March 26, 2020
Application Number:
20200094073
A cost function is constructed so as to guide an optimization process to achieve similar coverage for all targets simultaneously in a concurrent radiation treatment of multiple targets, so that a single scaling factor may be used in a plan normalization to achieve the desired coverage for all the targets. The cost function includes a component that favors a solution that attains similar target coverages for all targets, as well as a component that favors a solution that approaches the…
RADIATION THERAPY SYSTEM USING A DIGITAL TOMOSYNTHESIS PROCESS FOR NEAR REAL-TIME LOCALIZATION
Granted: January 30, 2020
Application Number:
20200030633
A method of radiation therapy comprises, while a gantry of a radiation therapy system rotates continuously in a first direction through a treatment arc from a first treatment delivery position to a second treatment delivery position, causing an imaging X-ray source mounted on the gantry to direct X-rays through a target volume and receiving a set of X-ray projection images from an X-ray imager mounted on the gantry; determining a current location of the target volume based on the set of…
SINGLE-PASS IMAGING AND RADIATION TREATMENT DELIVERY VIA AN EXTENDED ROTATION GANTRY
Granted: January 30, 2020
Application Number:
20200030636
A radiation therapy system delivers radiation treatment over a 360-degree arc and performs a prepended imaging process, in a single pass, via an extended rotation gantry. While rotating the gantry in one direction about a bore of the radiation system, the radiation system generates multiple images of a target volume disposed in the bore using an imaging X-ray source mounted on the gantry. Then while continuing to rotate the gantry in the same direction, the radiation system delivers a…
RADIATION THERAPY SYSTEM WITH MULTIPLE X-RAY IMAGERS FOR NEAR REAL-TIME LOCALIZATION
Granted: January 30, 2020
Application Number:
20200030634
A radiation therapy system is configured to enable imaging and treatment of a target volume during a single patient breath hold. The radiation system includes a rotating gantry on which are mounted a treatment-delivering X-ray source and multiple imaging X-ray sources and corresponding X-ray imaging devices. The multiple imaging X-ray sources and X-ray imaging devices enable the acquisition of volumetric image data for the target volume over a relatively short rotational arc, for example…
