Apparatus and method for real-time tracking of tissue structures
Granted: November 2, 2021
Patent Number:
11160537
A method and system are disclosed for radiosurgical treatment of moving tissues of the heart, including acquiring at least one volume of the tissue and acquiring at least one ultrasound data set, image or volume of the tissue using an ultrasound transducer disposed at a position. A similarity measure is computed between the ultrasound image or volume and the acquired volume or a simulated ultrasound data set, image or volume. A robot is configured in response to the similarity measure…
Clinical goal treatment planning and optimization
Granted: October 26, 2021
Patent Number:
11158408
An apparatus for developing an intensity-modulated radiation therapy treatment plan includes a memory that stores machine instructions and a processor that executes the machine instructions to receive a clinical goal associated with the treatment plan as a user input. The processor further executes the machine instructions to determine a plan objective based on the clinical goal, generate a cost function comprising a term based on the plan objective, and assign an initial value to a…
High DQE imaging device
Granted: October 26, 2021
Patent Number:
11156727
An imaging device includes: a scintillator layer; and an array of photodiode elements; wherein the scintillator layer is configured to receive radiation that has passed through the array of photodiode elements. An imaging device includes: a scintillator layer having a plurality of scintillator elements configured to convert radiation into photons; and an array of photodiode elements configured to receive photons from the scintillator layer, and generate electrical signals in response to…
Method and apparatus for performing irradiation time optimization for intensity modulated proton therapy during treatment planning while maintaining acceptable irradiation plan quality
Granted: October 26, 2021
Patent Number:
11154726
A computer implemented method of determining a resultant treatment plan for a proton radiation therapy system based on given dose volume constraints, wherein the resultant treatment plan is optimized for treatment time comprises accessing the dose volume constraints and range information, wherein the range information indicates acceptable deviations from the dose volume constraints. Based on the proton radiation therapy system, the method further comprises accessing machine configuration…
Blood-tissue surface based radiosurgical renal treatment planning
Granted: October 26, 2021
Patent Number:
11154725
Devices, systems, and methods for planning radiosurgical treatments for neuromodulating a portion of the renovascular system may be used to plan radiosurgical neuromodulation treatments for conditions or disease associated with elevated central sympathetic drive. The renal nerves may be located and targeted at the level of the ganglion and/or at postganglionic positions, as well as preganglionic positions. Target regions include the renal plexus, celiac ganglion, the superior mesenteric…
Streamlined, guided on-couch adaptive workflow
Granted: October 5, 2021
Patent Number:
11135448
Systems and methods for implementing an adaptive therapy workflow that minimizes time needed to create a session patient model, select an appropriate plan for the treatment session, and treat the patient.
Radiation treatment planning based on dose rate
Granted: September 14, 2021
Patent Number:
11116995
A dose rate-volume histogram is generated for a target volume. The dose rate-volume histogram can be stored in computer system memory and used to generate a radiation treatment plan. An irradiation time-volume histogram can also be generated for the target volume. The irradiation time-volume histogram can be stored in computer system memory and used to generate the radiation treatment plan.
Radiation therapy system using a digital tomosynthesis process for near real-time localization
Granted: September 7, 2021
Patent Number:
11110300
A method of radiation therapy comprises, while a gantry of a radiation therapy system rotates continuously in a first direction through a treatment arc from a first treatment delivery position to a second treatment delivery position, causing an imaging X-ray source mounted on the gantry to direct X-rays through a target volume and receiving a set of X-ray projection images from an X-ray imager mounted on the gantry; determining a current location of the target volume based on the set of…
Creating treatment field using initial field and patient specific geometry and achievable dose
Granted: August 31, 2021
Patent Number:
11103726
Methods and systems are provided for developing radiation therapy treatment plans. A treatment template with radiation fields can be chosen for a patient based on a tumor location. Static radiation field positions can be adjusted for the patient, while arc radiation fields may remain the same. Static radiation field positions can be adjusted using dose gradient, historical patient data, and other techniques.
Model based PBS optimization for flash therapy treatment planning and oncology information system
Granted: August 31, 2021
Patent Number:
11103727
A computing system comprising a central processing unit (CPU), and memory coupled to the CPU and having stored therein instructions that, when executed by the computing system, cause the computing system to execute operations to generate a radiation treatment plan. The operations include accessing a minimum prescribed dose to be delivered into and across the target, determining a number of beams and directions of the beams, and determining a beam energy for each of the beams, wherein the…
Method and system applications for push notification
Granted: August 24, 2021
Patent Number:
11102318
Embodiments of the present invention are directed to a method, system, and article of manufacture of a native notification center app that receive all types of push notifications. The push notification payload contains the URL to be launched when touched on the display of a mobile device and the custom data to be passed to the web application on launch. The push message sent to the notification center app and when the app is opened, which lists all the push notifications. When the user…
Heart tissue surface contour-based radiosurgical treatment planning
Granted: August 24, 2021
Patent Number:
11097127
A system that generates a three-dimensional model of a tissue surface, for example the inner surface of the heart from two-dimensional image data slices. On this surface, one or more pattern lines are drawn, e.g., by a physician using a user interface, to designate desired lesion(s) on the surface. From the pattern lines, a three-dimensional volume for a lesion can be determined using known constraints. Advantageously, the series of boundaries generated by the three-dimensional volume…
Systems, methods, and devices for real-time treatment verification using an electronic portal imaging device
Granted: August 17, 2021
Patent Number:
11090512
A radiation dose received by a patient from a radiation therapy system can be verified by acquiring a cine stream of image frames from an electronic portal imaging device (EPID) that is arranged to detect radiation exiting the patient during irradiation. The cine stream of EPID image frames can be processed in real-time to form exit images providing absolute dose measurements at the EPID (dose-to-water values), which is representative of the characteristics of the radiation received by…
System and method for biological treatment planning and decision support
Granted: August 17, 2021
Patent Number:
11090508
Embodiments of the present invention provide an integrated solution to radiotherapy treatment planning that enables accurate recording and accumulation of physical parameters as input (e.g., dose, dose rate, irradiation time per voxel, etc.). User-defined functions are evaluated to correlate the input parameters with 4D biological outcomes. The resulting biological parameters can be visualized as a biological outcome map to evaluate decisions, support decisions, and optimize decisions…
Scintillating glass pixelated imager
Granted: August 3, 2021
Patent Number:
11079499
In a method of making pixelated scintillators, a block of an amorphous scintillator material is divided into plural sections. The plural sections of the block are rejoined with plural first reflective septa to form an assembly. In the assembly, each of the plural first reflective septa separates two adjacent sections of the block. The assembly is then divided into plural sections in a way such that each of the plural sections of the block is divided into plural pixels. The plural…
Apparatus and method for real-time tracking of bony structures
Granted: August 3, 2021
Patent Number:
11076776
A method for measuring skin thickness. The method includes at a first 3D point on an outer surface of a patient, exposing the first point to near infrared (NIR) energy from an NIR source. The method includes measuring reflected energy emanating near the first 3D point, or beam incident point. The method includes determining a pattern of the reflected energy based on a distance from a center of the reflected energy, wherein the center is approximated by the first 3D point. The method…
Imaging-based self-adjusting radiation therapy systems, devices, and methods
Granted: July 13, 2021
Patent Number:
11058393
Systems, devices, and methods are presented for automatic tuning, calibration, and verification of radiation therapy systems comprising control elements configured to control parameters of the radiation therapy systems based on images obtained using electronic portal imaging devices (EPIDs) included in the radiation therapy system.
Radiation therapy planning using integrated model
Granted: July 6, 2021
Patent Number:
11056240
System and method for automatically generate therapy plan parameters by use of an integrate model with extended applicable regions. The integrated model integrates multiple predictive models from which a suitable predictive model can be selected automatically to perform prediction for a new patient case. The integrated model may operate to evaluate prediction results generated by each predictive model and the associated prediction reliabilities and selectively output a satisfactory…
Loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same
Granted: July 6, 2021
Patent Number:
11052050
Particles are provided for use in therapeutic and/or diagnostic procedures. The particles include poly[bis(trifluoroethoxy) phosphazene] and/or a derivatives thereof which may be present throughout the particles or within an outer coating of the particles. The particles can also include a core having a hydrogel formed from an acrylic-based polymer. Barium sulfate may also be provided to the core of the particles as a coating or absorbed within the core of the particles. The particles can…
Cone-beam computed tomography imaging devices, systems, and methods
Granted: June 29, 2021
Patent Number:
11045151
Cone-beam computer tomography systems, devices, and methods for image acquisition of large target volumes using partial scans.
