ATOMIC FORCE MICROSCOPY CONTROLLER AND METHOD
Granted: December 12, 2013
Application Number:
20130333076
A method for determining a loop response for an apparatus for an atomic force microscope is disclosed. The method comprises: determining a loop response for an on-surface movement of a cantilever over a frequency range; determining a loop response for an off-surface movement of the cantilever over the frequency range; and adjusting an output of the controller at a frequency based on the loop response for the off-surface movement. An atomic force microscopy system is disclosed.
TARGET ENRICHMENT AND LABELING FOR MULTI-KILOBASE DNA
Granted: December 5, 2013
Application Number:
20130323725
This disclosure provides a method comprising: a) clamping the top and bottom strands of a double stranded DNA molecule to produce a duplex in which the top and bottom strands are linked; b) denaturing the duplex to produce a denatured product; and c) renaturing the denatured product in the presence of a labeled oligonucleotide that is complementary to a sequence of nucleotides in the double stranded DNA molecule, thereby producing a D-loop-containing product. Kits for performing the…
PHASE NOISE EXTRACTION APPARATUS AND TECHNIQUE
Granted: December 5, 2013
Application Number:
20130322570
A phase noise extraction apparatus and technique that extracts phase noise induced by a component of a transmitter from a radio frequency (RF) signal and attenuates noise induced from other sources. The RF signal is digitized, modulation is removed, and the carrier is suppressed to provide a noise signal including the phase noise and the noise induced from the other sources. A complementary autocorrelation operation is applied to the noise signal to attenuate the noise from the other…
Power Device Analyzer
Granted: December 5, 2013
Application Number:
20130320959
A device analyzer for analyzing power devices. An example device analyzer comprises a collector supply to generate supply signal pulses with selected voltage or current levels and a supply signal pulse width at a high current. The supply signal pulses are applied at a collector supply source terminal when DUT is connected to conduct current between the collector supply source terminal and a collector supply common terminal. A supply switch closes or opens the DUT current path in narrow…
TRANSFORMER CORRECTION CIRCUIT AND TECHNIQUE FOR REDUCING CROSS-TALK CURRENT
Granted: November 28, 2013
Application Number:
20130314071
An apparatus and technique that reduces induced cross-talk current between transformer windings. The apparatus includes a transformer having a first secondary winding that provides a first voltage relative to earth ground, a second secondary winding that provides a second voltage relative to floating ground, and a shield disposed between the first and second secondary windings. A correction circuit connected to the first secondary winding is configured to generate a correction voltage.…
PRESSURIZABLE INJECTION SEAT
Granted: November 28, 2013
Application Number:
20130312499
An injection device (100) comprising: a housing (102) defining a space (104); a seat (110) located in said space (104), the seat (110) being configured for receiving a flow path element (116) capable of injecting a pressurized fluid into the injection device (100) through the seat (110); a pressure source (132) for pressurizing a medium in said space (104), thereby reducing the pressure difference between the pressurized fluid in said flow path element (116) and said medium.
FITTING ELEMENT WITH BIO-COMPATIBLE SEALING
Granted: November 14, 2013
Application Number:
20130298647
A fitting element is configured for coupling tubing to a fluidic device having a receiving cavity configured for receiving the fitting element, where the tubing has an inner contact surface of a biocompatible material, the inner contact surface being configured to contact a fluid to be conducted by the tubing, and the receiving cavity having a receiving contact surface of a bio-compatible material. The fitting element includes a first sealing element of a bio-compatible material…
OPTICAL EMISSION SYSTEM INCLUDING DICHROIC BEAM COMBINER
Granted: October 31, 2013
Application Number:
20130286390
An optical emission spectrometer system includes a light source and a dichroic beam combiner. The light source emits first light in a first direction and second light in a second direction different from the first direction. The dichroic beam combiner receives the first light via a first light path and the second light via a second light path, reflects a portion the first light into an entrance aperture of a light detection and measurement apparatus, and transmits a portion of the second…
LIQUID HANDLER WITH DUAL PIPETTING GROUPS
Granted: October 24, 2013
Application Number:
20130280145
An automated liquid handling system is disclosed. A system includes a first pipetting group, which includes at least one pipettor, movably arranged on a first arm; and a second pipetting group, which includes at least one pipettor, movably arranged on a second arm, wherein the first arm and the second arm are movably arranged on at least one track such that the first arm and the second arm can independently move along the at least one track while keeping the first arm parallel with the…
METHOD AND APPARATUS TO IMPROVE SIGNAL-TO-NOISE RATIO OF FT-IR SPECTROMETERS USING PULSED LIGHT SOURCE
Granted: October 3, 2013
Application Number:
20130258343
An optical spectroscopy method and apparatus increases signal to noise ratio of detected signals. Sample light passed through a sample includes attenuated light pulses and characteristic light located between the attenuated light pulses, the characteristic light formed by interaction between light pulses incident the sample and sample molecules. The attenuated light pulses are substantially removed from the sample light emerging from the sample prior to detection, to increase signal to…
Method and Apparatus for Tracking the Motion of Molecules in a Microscope
Granted: September 26, 2013
Application Number:
20130252272
An apparatus and method for measuring the mobility of molecules in a sample are disclosed. Molecules in a sample are tagged with a dye having active and inactive states that are generated by exposing dye to light of an activation wavelength and an inactivation wavelength, respectively, the activation wavelength being different from the inactivation wavelength. The sample is illuminated in a microscope with a light pattern that includes a first region in which the dye is activated and a…
MULTI-PATH BROADBAND AMPLIFIER
Granted: September 26, 2013
Application Number:
20130249637
An amplifier device having an extended bandwidth includes a DC coupled amplifier and multiple low noise amplifiers connected in series with one another and connected in parallel with at least a portion of the DC coupled amplifier. The DC coupled amplifier has a broad bandwidth, and each of the low noise amplifiers has a narrow bandwidth and a center frequency higher than a high end frequency of the broad bandwidth of the DC coupled amplifier. The extended bandwidth of the amplifier…
BALANCED VOLTAGE VARIABLE CAPACITOR DEVICE
Granted: September 5, 2013
Application Number:
20130229747
A variable capacitor device includes a stator and a rotor. The stator includes first and second stator plates separated by electrically insulating material. The rotor includes first and second rotor plates connected by a rod, the rotor being configured to move axially for adjusting alignment of the first rotor plate relative to the first stator plate and the second rotor plate relative to the second stator plate, respectively. The first stator plate and the first rotor plate form a first…
Method of Determining Thermodynamic and Kinetic Parameters from Measured Off Rates
Granted: August 29, 2013
Application Number:
20130225429
A method for measuring a property of a binding interaction between a capture agent and a binding partner for the capture agent is provided. In certain embodiments, this method comprises: a) contacting a population of particles that are linked to a capture agent with a substrate comprising a binding partner to produce capture agent/binding partner complexes, wherein the population of particles comprises first particles that are bound to a single molecule of the capture agent and second…
DOWNCONVERSION OF COMB SPECTRUM
Granted: August 29, 2013
Application Number:
20130225110
A downconverter mixes a first comb spectrum with a local oscillator signal to generate a second comb spectrum in a lower frequency range. The first comb spectrum comprises frequency components separated from each other according to a frequency spacing interval, and the LO signal has a frequency offset relative to the first comb spectrum, where the frequency offset is a rational fraction of the frequency spacing interval. The second comb spectrum comprises lower and upper sideband…
DIGITAL OSCILLOSCOPE COMPRISING MULTIPLE DATA ACQUISITION PATHWAYS
Granted: August 15, 2013
Application Number:
20130207641
A digital oscilloscope comprises a sampling unit configured to sample an input signal received from an oscilloscope probe to produce a first stream of digital samples, a first acquisition system configured to store and process the stream of digital samples to produce a first data set, a second acquisition system configured to store and process the first stream of digital samples independent of the first acquisition system to produce a second data set, and a display system configured to…
METHOD OF GENERATING INTERFERENCE SIGNALS AND DEVICE TO CARRY OUT SUCH A METHOD
Granted: August 8, 2013
Application Number:
20130202020
A method for generating interference signals and a device to carry out said method, in which an interference signal (1) is added in a signal combination and separation network (3) with a desired signal (4) that carries a test message, the sum signal being sent to a device being tested (5). The interference signal (1) is generated with a single source connected to a signal divider and conditioner block (7) that attenuates additional interference produced by the source of generation of…
CHARGE CORRECTION FOR PIEZOELECTRIC ACTUATOR
Granted: August 8, 2013
Application Number:
20130200751
A system comprises a voltage source, a piezoelectric material arranged in a first current path between the voltage source and a first reference voltage, a capacitor arranged in a second current path between the voltage source and a second reference voltage, and a correction circuit configured to adjust the first reference voltage to increase or decrease the current in the first current path according to the current in the second current path.
FERRULE CHUCK WITH SURFACE MICRO-GRIP
Granted: August 8, 2013
Application Number:
20130199981
A fitting for coupling a capillary to another component of a fluidic device is disclosed. The fitting includes a ferrule configured for enclosing a front part of the capillary and for contributing to a fluidic sealing between the fitting and the other component; a ferrule chuck configured for enclosing a back part of the capillary; and a housing configured for accommodating at least a part of the ferrule chuck and for pushing the ferrule chuck against the ferrule.
SYSTEM FOR MEASURING RESIDUAL PHASE NOISE
Granted: August 1, 2013
Application Number:
20130197848
A system for measuring residual phase noise of a device under test (DUT) includes first and second signal sources, first and second receivers, and a processor. The first signal source generates a first signal to be input to the DUT as a stimulus signal and provides a second signal that is phase coherent with the first signal. The second signal source receives the second signal and generates a reference signal based on the second signal, which is phase coherent with the stimulus signal.…
